Chewed Versus Integral Pill of Ticagrelor
Last updated on July 2021Recruitment
- Recruitment Status
- Active, not recruiting
- Estimated Enrollment
- 130
Summary
- Conditions
- Percutaneous Coronary Intervention
- Type
- Interventional
- Phase
- Phase 4
- Design
- Allocation: RandomizedIntervention Model: Parallel AssignmentMasking: None (Open Label)Primary Purpose: Treatment
Participation Requirements
- Age
- Between 18 years and 89 years
- Gender
- Both males and females
Description
Hypothesis The primary question the investigators propose to answer is whether all patients undergoing PCI with stent deployment who receive chewed ticagrelor will demonstrate more rapid drug absorption and decreased platelet reactivity as compared to integral pill form 1 hour after drug administrat...
Hypothesis The primary question the investigators propose to answer is whether all patients undergoing PCI with stent deployment who receive chewed ticagrelor will demonstrate more rapid drug absorption and decreased platelet reactivity as compared to integral pill form 1 hour after drug administration. Secondary Hypotheses: Major adverse cardiac and cerebrovascular event (MACCE) rate at 30 days and 1 year. Death Repeat myocardial infarction Need for urgent revascularization Cerebrovascular accident Rate of stent thrombosis and in-stent stenosis at 30 days and 1 year. Bleeding: Defined as major, minor, or minimal bleeding based on TIMI criteria.
Tracking Information
- NCT #
- NCT03708588
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Thomas F Wilson, MD Aurora Health Care
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