APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Kidney Disease, Chronic
- Kidney Diseases
- Kidney Failure
- Type
- Observational
- Design
- Observational Model: CohortTime Perspective: Prospective
Participation Requirements
- Age
- Younger than 125 years
- Gender
- Both males and females
Description
The National Institutes of Health (NIH)-sponsored collaborative APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO) is charged with prospectively assessing the effects of renal-risk variants (RRVs) in the apolipoprotein L1 gene (APOL1) on outcomes for kidneys from donors with recent Afr...
The National Institutes of Health (NIH)-sponsored collaborative APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO) is charged with prospectively assessing the effects of renal-risk variants (RRVs) in the apolipoprotein L1 gene (APOL1) on outcomes for kidneys from donors with recent African ancestry and the recipients of their kidneys, after deceased- and living-donor renal transplantation. For the purposes of APOLLO, recent African ancestry is defined as individuals with similar genetic make-up to those currently residing in Africa. APOLLO will also study the impact of APOL1 RRVs on the health of living kidney donors with recent African ancestry.
Tracking Information
- NCT #
- NCT03615235
- Collaborators
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- National Institute on Minority Health and Health Disparities (NIMHD)
- National Institute of Allergy and Infectious Diseases (NIAID)
- Investigators
- Principal Investigator: Barry I. Freedman, MD Wake Forest University Health Sciences Principal Investigator: David M. Reboussin, PhD Wake Forest University Health Sciences Study Director: Paul L. Kimmel, MD Natl Institute of Diabetes, Digestive & Kidney Diseases Study Chair: Marva Moxey-Mims, MD Children's Natl Health System; George Washington Univ Sch of Med and Health Serv
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