Donor Stem Cell Transplantation Using ?/?+ T-lymphocyte Depleted Grafts From HLA Mismatched Donors
Last updated on July 2021Recruitment
- Recruitment Status
- Active, not recruiting
- Estimated Enrollment
- 38
Summary
- Conditions
- Acute Lymphoid Leukemia (ALL)
- Acute Myeloid Leukemia (AML)
- Chronic Lymphocytic Leukemia
- Chronic Myeloid Leukemia (CML)
- Hodgkin Lymphoma
- Non Hodgkin Lymphoma
- Type
- Interventional
- Phase
- Phase 2
- Design
- Allocation: Non-RandomizedIntervention Model: Parallel AssignmentIntervention Model Description: Participants will receive one of three myeloablative conditioning regimens followed by a Alpha/beta+ T-cell depleted peripheral blood stem cell product and short course tacrolimus. Donors are HLA mismatched unrelated adults or haploidentical family members.Masking: None (Open Label)Primary Purpose: Treatment
Participation Requirements
- Age
- Younger than 65 years
- Gender
- Both males and females
Description
Not Provided
Not Provided
Tracking Information
- NCT #
- NCT03615105
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Brian Shaffer, MD Memorial Sloan Kettering Cancer Center
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