Transcranial Direct Current Stimulation as a Neuroprotection in Acute Stroke
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
Summary
- Conditions
- Stroke Acute
- Type
- Interventional
- Phase
- Not Applicable
- Design
- Allocation: RandomizedIntervention Model: Sequential AssignmentIntervention Model Description: Traditional 3+3 (rule-based, modified Fibonacci) dose escalation designMasking: Triple (Participant, Care Provider, Outcomes Assessor)Primary Purpose: Treatment
Participation Requirements
- Age
- Between 18 years and 125 years
- Gender
- Both males and females
Description
This is a single center, sham-controlled, dose escalation study where cathodal tDCS is delivered to threatened but not yet irreversibly damaged (penumbral) tissue in patients with large vessel occlusion who are not eligible for blood flow restoring recanalization procedures. Patients will be randomi...
This is a single center, sham-controlled, dose escalation study where cathodal tDCS is delivered to threatened but not yet irreversibly damaged (penumbral) tissue in patients with large vessel occlusion who are not eligible for blood flow restoring recanalization procedures. Patients will be randomized in a 3:1 design, to cathodal versus sham (control) stimulation, at each six designed dose tiers. The dose tiers will be increasing in both intensity and duration of the stimulation. The occurrence of symptomatic intracranial hemorrhage will determine the pace of the escalation through the dose tiers.
Tracking Information
- NCT #
- NCT03574038
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Mersedeh Bahr Hosseini, MD University of California, Los Angeles
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