Peanut and Tree Nut Desensitization
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Peanut Allergy
- Tree Nut Allergy
- Type
- Interventional
- Phase
- Not Applicable
- Design
- Allocation: RandomizedIntervention Model: Parallel AssignmentIntervention Model Description: Randomized controlled trialMasking: Single (Participant)Masking Description: Participants will be randomized to one of three groups: a control group that will receive no treatment, a low-dose group and a high dose group. Participants in the latter two groups will be blinded as to what group they have been assignedPrimary Purpose: Treatment
Participation Requirements
- Age
- Between 2 years and 40 years
- Gender
- Both males and females
Description
The investigators are proposing to initiate a study assessing a common desensitization protocol for peanut/tree nut allergy. This study would enable the investigators to better determine the potential benefit of desensitization in individuals with peanut/tree nut allergy. More specifically, the inve...
The investigators are proposing to initiate a study assessing a common desensitization protocol for peanut/tree nut allergy. This study would enable the investigators to better determine the potential benefit of desensitization in individuals with peanut/tree nut allergy. More specifically, the investigators will address the following research objectives: Objectives A. To develop a protocols for peanut/tree nut desensitization with high (300mg) and low (30mg maintenance dose). B. To determine the rate of desensitization to peanut/tree nut. C. To characterize predictors of successful desensitization. D. To characterize molecular mechanisms involved in the process of desensitization These objectives will be evaluated through a randomized controlled trial
Tracking Information
- NCT #
- NCT03532360
- Collaborators
- Julia Upton, Hospital for Sick Children, University of Toronto
- Investigators
- Not Provided
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