Network-Level Effects of Nitrous Oxide in the Human Brain
Last updated on July 2021Recruitment
- Recruitment Status
- Completed
- Estimated Enrollment
- 22
Summary
- Conditions
- Healthy
- Type
- Interventional
- Phase
- Phase 4
- Design
- Allocation: N/AIntervention Model: Single Group AssignmentMasking: None (Open Label)Primary Purpose: Basic Science
Participation Requirements
- Age
- Between 21 years and 40 years
- Gender
- Both males and females
Description
The objective of this study is to identify the network transformations that account for the analgesic effects of nitrous oxide. Our hypothesis is that analgesic doses of nitrous oxide increase network efficiency and disrupt normal pain processingOur approach is to administer subanesthetic nitrous ox...
The objective of this study is to identify the network transformations that account for the analgesic effects of nitrous oxide. Our hypothesis is that analgesic doses of nitrous oxide increase network efficiency and disrupt normal pain processingOur approach is to administer subanesthetic nitrous oxide during the acquisition of fMRI (functional magnetic resonance imaging) and EEG (electroencephalogram).
Tracking Information
- NCT #
- NCT03435055
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Richard Harris, PhD Associate Professor of Anesthesiology and Associate Professor of Internal Medicine
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