Transradial Selective Catheterization of the Celiac Artery in Obese Patients
Last updated on July 2021Recruitment
- Recruitment Status
- Completed
- Estimated Enrollment
- 100
Summary
- Conditions
- Obesity
- Type
- Interventional
- Phase
- Not Applicable
- Design
- Allocation: N/AIntervention Model: Single Group AssignmentIntervention Model Description: Feasibility pilot studyMasking: None (Open Label)Primary Purpose: Other
Participation Requirements
- Age
- Between 18 years and 125 years
- Gender
- Both males and females
Description
RATIONALE: A significant proportion of patients referred to IUCPQ-UL catheterization laboratory are overweight (body mass index >25 kg/m²). Ongoing research and early clinical experience suggest that embolization of the left gastric artery could drastically reduce ghrelin levels and be associated wi...
RATIONALE: A significant proportion of patients referred to IUCPQ-UL catheterization laboratory are overweight (body mass index >25 kg/m²). Ongoing research and early clinical experience suggest that embolization of the left gastric artery could drastically reduce ghrelin levels and be associated with significant weight loss. In obese patients, catheterization using femoral artery access is associated with higher risks of vascular complications and peri-procedural bleeding compared to a radial artery approach. Given the anatomy (angle) of the celiac artery, selective catheterization of the celiac and left gastric arteries remains challenging, especially in obese patients. Before studying the effects of bariatric embolization, more data regarding the access of the left gastric artery is necessary. HYPOTHESES: Transradial angiography of the celiac artery/left gastric artery is feasible and safe. Given the angulation of celiac artery, catheterization through a radial approach could be simpler. Selective angiography of the celiac artery and the left gastric artery can be performed in the setting of uncomplicated coronary angiography/percutaneous coronary intervention (PCI). Detailed anatomy of the celiac artery and its branches can be visualized by selective transradial angiography. OBJECTIVES: The primary objective is to demonstrate the feasibility and safety of performing selective angiography of the celiac artery using a transradial approach in obese patients referred for diagnostic coronary angiography and/or PCI. The secondary objective is to observe anatomical variations of the celiac artery and the left gastric artery. STUDY DESIGN: > A prospective pilot study performed at Quebec Heart & Lung Institute (Institut Universitaire de Cardiologie et de Pneumologie de Québec - Université Laval; IUCPQ-UL).
Tracking Information
- NCT #
- NCT03434665
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Olivier F Bertrand, MD PhD IUCPQ-UL and Laval University
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