Swedish Multicenter Trial of Outpatient Prevention of Leg Clots
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- 1300
Summary
- Conditions
- Achilles Tendon Rupture
- Ankle Fractures
- Venous Thromboembolism
- Type
- Interventional
- Phase
- Not Applicable
- Design
- Allocation: RandomizedIntervention Model: Parallel AssignmentMasking: Double (Care Provider, Outcomes Assessor)Primary Purpose: Prevention
Participation Requirements
- Age
- Between 18 years and 75 years
- Gender
- Both males and females
Description
The proposed intervention, intermittent pneumatic compression (IPC) is an evidence-based prevention for VTE in hospitalized patients and used in daily practice. IPC is, however, not currently used on outpatients and it is currently unknown if it reduces the risk of VTE during long term leg-immobiliz...
The proposed intervention, intermittent pneumatic compression (IPC) is an evidence-based prevention for VTE in hospitalized patients and used in daily practice. IPC is, however, not currently used on outpatients and it is currently unknown if it reduces the risk of VTE during long term leg-immobilization. Plaster cast and orthosis treatments are currently used in daily practice on Achilles tendon ruptures and ankle fractures. At present there is no consensus about using VTE prophylaxis in leg-immobilized patients. Since pharmacoprophylaxis has shown low- or no VTE preventive effects in leg-immobilization, is not recommended by some guidelines. Furthermore, since all patients will undergo clinical examinations and have DVT-screening performed with compression Doppler ultrasound (CDU) removal of leg immobilization this will comprise an extra security for the included patients to detect a VTE. If a VTE is detected clinical guidelines will be followed by initiating chemical VTE-treatment.
Tracking Information
- NCT #
- NCT03259204
- Collaborators
- Uppsala University Hospital
- Stockholm South General Hospital
- Sahlgrenska University Hospital, Sweden
- Danderyd Hospital
- University Hospital, Linkoeping
- Visby lasarett
- Karlstad Central Hospital
- Region Örebro County
- Gävle Hospital
- Höglandssjukhuset Eksjö
- Norrtälje Hospital
- Östersunds Hospital
- Uddevalla Hospital
- Helsingborgs Hospital
- Skövde Hospital
- Investigators
- Principal Investigator: Paul W Ackermann, MD, PhD Karolinska University Hospital, 171 76 Stockholm, SWEDEN