Recruitment

Recruitment Status
Recruiting
Estimated Enrollment
1300

Summary

Conditions
  • Achilles Tendon Rupture
  • Ankle Fractures
  • Venous Thromboembolism
Type
Interventional
Phase
Not Applicable
Design
Allocation: RandomizedIntervention Model: Parallel AssignmentMasking: Double (Care Provider, Outcomes Assessor)Primary Purpose: Prevention

Participation Requirements

Age
Between 18 years and 75 years
Gender
Both males and females

Description

The proposed intervention, intermittent pneumatic compression (IPC) is an evidence-based prevention for VTE in hospitalized patients and used in daily practice. IPC is, however, not currently used on outpatients and it is currently unknown if it reduces the risk of VTE during long term leg-immobiliz...

The proposed intervention, intermittent pneumatic compression (IPC) is an evidence-based prevention for VTE in hospitalized patients and used in daily practice. IPC is, however, not currently used on outpatients and it is currently unknown if it reduces the risk of VTE during long term leg-immobilization. Plaster cast and orthosis treatments are currently used in daily practice on Achilles tendon ruptures and ankle fractures. At present there is no consensus about using VTE prophylaxis in leg-immobilized patients. Since pharmacoprophylaxis has shown low- or no VTE preventive effects in leg-immobilization, is not recommended by some guidelines. Furthermore, since all patients will undergo clinical examinations and have DVT-screening performed with compression Doppler ultrasound (CDU) removal of leg immobilization this will comprise an extra security for the included patients to detect a VTE. If a VTE is detected clinical guidelines will be followed by initiating chemical VTE-treatment.

Tracking Information

NCT #
NCT03259204
Collaborators
  • Uppsala University Hospital
  • Stockholm South General Hospital
  • Sahlgrenska University Hospital, Sweden
  • Danderyd Hospital
  • University Hospital, Linkoeping
  • Visby lasarett
  • Karlstad Central Hospital
  • Region Örebro County
  • Gävle Hospital
  • Höglandssjukhuset Eksjö
  • Norrtälje Hospital
  • Östersunds Hospital
  • Uddevalla Hospital
  • Helsingborgs Hospital
  • Skövde Hospital
Investigators
Principal Investigator: Paul W Ackermann, MD, PhD Karolinska University Hospital, 171 76 Stockholm, SWEDEN