The Role of the Gut Microbiota in Estrogen Metabolism and Dietary Flax as a Potential Modulator.
Last updated on July 2021Recruitment
- Recruitment Status
- Active, not recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Menopause
- Type
- Interventional
- Phase
- Not Applicable
- Design
- Allocation: RandomizedIntervention Model: Parallel AssignmentMasking: Single (Outcomes Assessor)Masking Description: Biological samples will be masked for endpoint analysisPrimary Purpose: Basic Science
Participation Requirements
- Age
- Between 20 years and 40 years
- Gender
- Only males
Description
This pilot study will begin to address whether gut microbiota change with estrogen suppression. Specifically, the investigators will test whether gut microbial diversity and abundance change in response to estrogen suppression and consumption of dietary flaxseed. To test this possibility the investi...
This pilot study will begin to address whether gut microbiota change with estrogen suppression. Specifically, the investigators will test whether gut microbial diversity and abundance change in response to estrogen suppression and consumption of dietary flaxseed. To test this possibility the investigators will recruit premenopausal women (age 20-40 years old)and collect fecal samples before and after 1 month of estrogen suppression with GnRH agonist. The investigators will analyze the gut microbiota in response to estrogen loss and whether this differs with the consumption of flaxseed.
Tracking Information
- NCT #
- NCT03183102
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Kimberly Cox-york, PhD Colorado State University
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