Perioperative Hypothermia and Myocardial Injury After Non-cardiac Surgery
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Hypothermia; Anesthesia
- Myocardial Injury
- Perioperative Care
- Surgery- Complications
- Type
- Interventional
- Phase
- Not Applicable
- Design
- Allocation: RandomizedIntervention Model: Parallel AssignmentMasking: Single (Outcomes Assessor)Masking Description: To maintain blinding, the anesthesia record will be sealed in an opaque envelope before patients leave the post-anesthesia care unit. The envelope will be marked "Do not open until [date 35 days after surgery]." Some hospitals will have electronic records; in those cases, we will ask investigators evaluating postoperative outcomes not to access the anesthesia record.Primary Purpose: Supportive Care
Participation Requirements
- Age
- Between 45 years and 125 years
- Gender
- Both males and females
Description
Hypothermia increases sympathetic activation, promotes tachycardia, and causes hypertension - all of which may increase the risk of myocardial injury. Moderate perioperative hypothermia is now uncommon, but mild hyperthermia (?35.5°C) remains common. Whether aggressive warming to a truly normothermi...
Hypothermia increases sympathetic activation, promotes tachycardia, and causes hypertension - all of which may increase the risk of myocardial injury. Moderate perioperative hypothermia is now uncommon, but mild hyperthermia (?35.5°C) remains common. Whether aggressive warming to a truly normothermic level (?37°C) improves outcomes remains unknown.
Tracking Information
- NCT #
- NCT03111875
- Collaborators
- Not Provided
- Investigators
- Not Provided
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