Characterization of Human Autoantibody Titers After Central Nervous System Insult
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Brain Injuries, Traumatic
- Intracranial Neoplasm
- Spinal Cord Trauma
- Type
- Observational
- Design
- Observational Model: CohortTime Perspective: Prospective
Participation Requirements
- Age
- Between 18 years and 125 years
- Gender
- Both males and females
Description
Study Objectives: We aim to: Quantitate CNS autoantibody development in human blood using ELISA after human brain injury, spinal cord injury, and intra-axial brain surgeries. We also aim to characterize the temporal course of this response. Characterize how CNS autoantibody levels correlate with spe...
Study Objectives: We aim to: Quantitate CNS autoantibody development in human blood using ELISA after human brain injury, spinal cord injury, and intra-axial brain surgeries. We also aim to characterize the temporal course of this response. Characterize how CNS autoantibody levels correlate with specific injury patterns as well as radiographic and clinical measures of injury severity. Determine how intercurrent infection and a history of prior CNS insult affects the temporal course and magnitude of autoantibody production.
Tracking Information
- NCT #
- NCT03089749
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Gregory WJ Hawryluk, MD, Ph.D. University of Utah
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