Umbilical Cord Blood Transplantation From Unrelated Donors
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Acute Leukemia
- Aplastic Anemia
- Chronic Leukemia
- Congenital Hematological Disorder
- Immune Deficiency Disorder
- Lymphoma
- Metabolism Disorder
- Multiple Myeloma
- Myelodysplastic Syndromes
- Solid Tumor
- Type
- Interventional
- Phase
- Phase 1
- Design
- Allocation: Non-RandomizedIntervention Model: Parallel AssignmentMasking: None (Open Label)Primary Purpose: Treatment
Participation Requirements
- Age
- Younger than 275 years
- Gender
- Both males and females
Description
This study is a single-center treatment protocol with four possible preparative regimens, designed to validate the process of umbilical cord blood stem cell transplantation at our institution. Enrolled patients will receive chemotherapy +/-total body radiation as a pre-transplant conditioning regime...
This study is a single-center treatment protocol with four possible preparative regimens, designed to validate the process of umbilical cord blood stem cell transplantation at our institution. Enrolled patients will receive chemotherapy +/-total body radiation as a pre-transplant conditioning regimen. Patients will then receive cord blood stem cells followed by GvHD prophylaxis that will include Tacrolimus and Mycophenolate Mofetil, or Cyclosporin A and Methylprednisolone. Multiple data points will be collected prior to, during, and following transplantation to ensure safety of the process and to evaluate the stated objectives.
Tracking Information
- NCT #
- NCT03016806
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Jane L Liesveld, MD Medical Director, Blood & Marrow Transplant Unit
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