Etiology, Epidemiology and Prognostics of AKI

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To investigate the relationship between preexisting protein-energy wasting (PEW) and adverse outcomes in patients with AKI. To evaluate the association of serum nutritional variables and prognosis of AKI. Given the different half-lives of serum nutritional markers, we hypothesized that the utility o...

To investigate the relationship between preexisting protein-energy wasting (PEW) and adverse outcomes in patients with AKI. To evaluate the association of serum nutritional variables and prognosis of AKI. Given the different half-lives of serum nutritional markers, we hypothesized that the utility of serum nutritional variables as prognostic predictors may differ in early death (<7 days) and late death (>7 days, <28 days) patients. To investigate the various kinds of uremic toxins in AKI, furthermore, to evaluate the relationship between uremic toxins, especially protein bound toxins, and short- or long-term mortality in AKI patients. To investigate the mineral bone disorders in AKI,and to evaluate whether these markers would role as prognostic predictors of AKI. Several risk factors of mortality in AKI,such as markers of PEW, inflammation and serum creatinine,have been used; however, no single indicator is considered to be a "gold standard."

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