Recruitment

Recruitment Status
Recruiting
Estimated Enrollment
Same as current

Summary

Conditions
  • Aging
  • Cardiovascular Disease
  • Circadian Dysregulation
  • Obesity
Design
Observational Model: CohortTime Perspective: Prospective

Participation Requirements

Age
Between 20 years and 125 years
Gender
Both males and females

Description

The objective of this observational study is the follow-up of 2000 adult obesity (BMI ? 35 and 24-35 kg/m2) and non-obese subjects with annual follow-up for 10 years. Clinical data, biochemistry, and biological samples (serum, DNA, RNA, white blood cells) will be collected and stored. Adipose tissue...

The objective of this observational study is the follow-up of 2000 adult obesity (BMI ? 35 and 24-35 kg/m2) and non-obese subjects with annual follow-up for 10 years. Clinical data, biochemistry, and biological samples (serum, DNA, RNA, white blood cells) will be collected and stored. Adipose tissues will be collected if participants received liposuction, plastic surgery, bariatric surgery, dermatological procedure, intra-abdominal operation, and cardiovascular surgery. Questionnaires will be obtained with special nurse including sleep quality, chronotypes, and circadian activities. During follow up period, major adverse cardiovascular events will be monitored. The investigators anticipate that the results generated from the study will provide valuable data to a better understanding of the relationships between obesity, circadian rhythm, and aging.

Tracking Information

NCT #
NCT02674230
Collaborators
Not Provided
Investigators
Principal Investigator: Chao-Yung Wang, MD Chang Gung Memorial Hospital