Recruitment

Recruitment Status
Enrolling by invitation
Estimated Enrollment
30

Summary

Conditions
Pancreatic Neoplasms
Type
Observational
Design
Observational Model: CohortTime Perspective: Prospective

Participation Requirements

Age
Between 18 years and 125 years
Gender
Both males and females

Description

This is an observational study of patients with pancreatic cancer to identify genomic expression differences obtained from their circulating tumor cells between exceptional responders and non-responders to standard of care chemotherapy. This study requires a 10 mL heparinized peripheral blood sample...

This is an observational study of patients with pancreatic cancer to identify genomic expression differences obtained from their circulating tumor cells between exceptional responders and non-responders to standard of care chemotherapy. This study requires a 10 mL heparinized peripheral blood sample from each study participant at the time of enrollment to isolate, enrich and profile circulating tumor cells. Data analysis of the gene expression profile will define genomic patterns using Nearest Template Prediction for a predetermined panel of therapeutic agents based on standard of care. Chemotherapy selection is physician-choice. Information regarding disease progression will be gathered. Data analysis will be performed in study participants in the setting of ongoing disease progression.

Tracking Information

NCT #
NCT02555735
Collaborators
  • Memorial Sloan Kettering Cancer Center
  • Weill Medical College of Cornell University
  • The Pancreatic Cancer Treatment Center of Los Angeles
Investigators
Study Director: Brian McCarthy, PhD Adera Labs