Retinoic Acid Homeostasis in Neuropsychiatric Diseases
Last updated on July 2021Recruitment
- Recruitment Status
- Unknown status
- Estimated Enrollment
- 128
Summary
- Conditions
- Alcoholism
- Alzheimer's Disease
- Major Depression
- Schizophrenia
- Type
- Observational
- Design
- Observational Model: Case-ControlTime Perspective: Prospective
Participation Requirements
- Age
- Between 18 years and 65 years
- Gender
- Both males and females
Description
Retinoids comprise of a group of small-molecule derivatives of Vitamin A with retinoic acid (RA) representing the biologically most active endogenous form. RA has multiple functions central nervous system (CNS). It is hypothesized, that local RA homeostasis is functionally involved in the pathophysi...
Retinoids comprise of a group of small-molecule derivatives of Vitamin A with retinoic acid (RA) representing the biologically most active endogenous form. RA has multiple functions central nervous system (CNS). It is hypothesized, that local RA homeostasis is functionally involved in the pathophysiology of numerous neuropsychiatric diseases.
Tracking Information
- NCT #
- NCT02439099
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Isabella Heuser, MD, PhD Chair: Department of Psychiatry, Charité, CBF