Genetic Causes of FSGS, Nephrotic Syndrome, or Kidney Failure
Last updated on April 2022Recruitment
- Recruitment Status
- Active, not recruiting
Inclusion Criteria
- Family members of a person with FSGS, NS, kidney failure, or unexplained protein in their urine
- Subjects with FSGS (focal segmental glomerulosclerosis)
- Healthy volunteers
- ...
- Family members of a person with FSGS, NS, kidney failure, or unexplained protein in their urine
- Subjects with FSGS (focal segmental glomerulosclerosis)
- Healthy volunteers
- Subjects with unexplained kidney failure (have had a transplant or on dialysis)
- Subjects with NS (nephrotic syndrome)
- Subjects with unexplained proteinuria
Exclusion Criteria
- Patients who already know the genetic cause of their kidney disease
- Patients whose kidney disease is already explained by another syndrome such as (Branchio Oto Renal Syndrome or Alports syndrome)
- Patients who already know the genetic cause of their kidney disease
- Patients whose kidney disease is already explained by another syndrome such as (Branchio Oto Renal Syndrome or Alports syndrome)
Summary
- Conditions
- End Stage Renal Disease
- Focal Segmental Glomerulosclerosis
- Kidney Failure
- Nephrotic Syndrome
- Unexplained Proteinuria
- Type
- Observational
- Design
- Observational Model: Family-Based
- Time Perspective: Prospective
Participation Requirements
- Age
- Younger than 125 years
- Gender
- Both males and females
Description
The investigators welcome anyone (with or without a family history) with unexplained, non syndromic FSGS, nephrotic syndrome, or proteinuria to join the study. Participation involves a saliva (or blood if it is preferable) sample and urine sample (if applicable). There is no cost to participate and ...
The investigators welcome anyone (with or without a family history) with unexplained, non syndromic FSGS, nephrotic syndrome, or proteinuria to join the study. Participation involves a saliva (or blood if it is preferable) sample and urine sample (if applicable). There is no cost to participate and the study can be done from home in most cases.
Inclusion Criteria
- Family members of a person with FSGS, NS, kidney failure, or unexplained protein in their urine
- Subjects with FSGS (focal segmental glomerulosclerosis)
- Healthy volunteers
- ...
- Family members of a person with FSGS, NS, kidney failure, or unexplained protein in their urine
- Subjects with FSGS (focal segmental glomerulosclerosis)
- Healthy volunteers
- Subjects with unexplained kidney failure (have had a transplant or on dialysis)
- Subjects with NS (nephrotic syndrome)
- Subjects with unexplained proteinuria
Exclusion Criteria
- Patients who already know the genetic cause of their kidney disease
- Patients whose kidney disease is already explained by another syndrome such as (Branchio Oto Renal Syndrome or Alports syndrome)
- Patients who already know the genetic cause of their kidney disease
- Patients whose kidney disease is already explained by another syndrome such as (Branchio Oto Renal Syndrome or Alports syndrome)
Tracking Information
- NCT #
- NCT02194582
- Collaborators
- National Institutes of Health (NIH)
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- United States Department of Defense
- Investigators
- Principal Investigator: Martin R Pollak, MD Beth Israel Deaconess Medical Center
- Martin R Pollak, MD Beth Israel Deaconess Medical Center
Get Well Soon