Recruitment

Recruitment Status
Active, not recruiting

Inclusion Criterias

Subjects with FSGS (focal segmental glomerulosclerosis)
Healthy volunteers
Subjects with unexplained proteinuria
...
Subjects with FSGS (focal segmental glomerulosclerosis)
Healthy volunteers
Subjects with unexplained proteinuria
Family members of a person with FSGS, NS, kidney failure, or unexplained protein in their urine
Subjects with unexplained kidney failure (have had a transplant or on dialysis)
Subjects with NS (nephrotic syndrome)

Exclusion Criterias

Patients whose kidney disease is already explained by another syndrome such as (Branchio Oto Renal Syndrome or Alports syndrome)
Patients who already know the genetic cause of their kidney disease
Patients whose kidney disease is already explained by another syndrome such as (Branchio Oto Renal Syndrome or Alports syndrome)
Patients who already know the genetic cause of their kidney disease

Summary

Conditions
  • End Stage Renal Disease
  • Focal Segmental Glomerulosclerosis
  • Kidney Failure
  • Nephrotic Syndrome
  • Unexplained Proteinuria
Type
Observational
Design
  • Observational Model: Family-Based
  • Time Perspective: Prospective

Participation Requirements

Age
Younger than 125 years
Gender
Both males and females

Description

The investigators welcome anyone (with or without a family history) with unexplained, non syndromic FSGS, nephrotic syndrome, or proteinuria to join the study. Participation involves a saliva (or blood if it is preferable) sample and urine sample (if applicable). There is no cost to participate and ...

The investigators welcome anyone (with or without a family history) with unexplained, non syndromic FSGS, nephrotic syndrome, or proteinuria to join the study. Participation involves a saliva (or blood if it is preferable) sample and urine sample (if applicable). There is no cost to participate and the study can be done from home in most cases.

Inclusion Criterias

Subjects with FSGS (focal segmental glomerulosclerosis)
Healthy volunteers
Subjects with unexplained proteinuria
...
Subjects with FSGS (focal segmental glomerulosclerosis)
Healthy volunteers
Subjects with unexplained proteinuria
Family members of a person with FSGS, NS, kidney failure, or unexplained protein in their urine
Subjects with unexplained kidney failure (have had a transplant or on dialysis)
Subjects with NS (nephrotic syndrome)

Exclusion Criterias

Patients whose kidney disease is already explained by another syndrome such as (Branchio Oto Renal Syndrome or Alports syndrome)
Patients who already know the genetic cause of their kidney disease
Patients whose kidney disease is already explained by another syndrome such as (Branchio Oto Renal Syndrome or Alports syndrome)
Patients who already know the genetic cause of their kidney disease

Locations

Boston, Massachusetts, 02215
Boston, Massachusetts, 02215

Tracking Information

NCT #
NCT02194582
Collaborators
  • National Institutes of Health (NIH)
  • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
  • United States Department of Defense
Investigators
  • Principal Investigator: Martin R Pollak, MD Beth Israel Deaconess Medical Center
  • Martin R Pollak, MD Beth Israel Deaconess Medical Center