Recruitment

Recruitment Status
Completed

Inclusion Criterias

subjects who had IFG (100≤ fasting glucose <126 mg/dL)
or newly diagnosed type-2 diabetes (fasting glucose ≥126 mg/dL)
subjects who had IFG (100≤ fasting glucose <126 mg/dL)
or newly diagnosed type-2 diabetes (fasting glucose ≥126 mg/dL)

Exclusion Criterias

pregnancy or lactation
current and/or past history of cardiovascular disease including angina
taking medications or supplements
...
pregnancy or lactation
current and/or past history of cardiovascular disease including angina
taking medications or supplements
thyroid or pituitary disease
liver or kidney dysfunction

Summary

Conditions
  • Prediabetes
  • Type-2 Diabetes
Type
Interventional
Phase
Phase 2
Design
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: None (Open Label)
  • Primary Purpose: Basic Science

Participation Requirements

Age
Between 40 years and 70 years
Gender
Both males and females

Description

Eighty nonobese patients (aged 40-70 years) with prediabetes or newly diagnosed type-2 diabetes were randomly assigned to a control group (normal diet with refined rice) or a whole-grain group (replacement of refined rice with whole-grains and legumes). This dietary intervention replaced approximate...

Eighty nonobese patients (aged 40-70 years) with prediabetes or newly diagnosed type-2 diabetes were randomly assigned to a control group (normal diet with refined rice) or a whole-grain group (replacement of refined rice with whole-grains and legumes). This dietary intervention replaced approximately 7% of carbohydrate-derived energy with approximately 4% of protein-derived energy and approximately 3% of fat-derived energy.

Inclusion Criterias

subjects who had IFG (100≤ fasting glucose <126 mg/dL)
or newly diagnosed type-2 diabetes (fasting glucose ≥126 mg/dL)
subjects who had IFG (100≤ fasting glucose <126 mg/dL)
or newly diagnosed type-2 diabetes (fasting glucose ≥126 mg/dL)

Exclusion Criterias

pregnancy or lactation
current and/or past history of cardiovascular disease including angina
taking medications or supplements
...
pregnancy or lactation
current and/or past history of cardiovascular disease including angina
taking medications or supplements
thyroid or pituitary disease
liver or kidney dysfunction

Locations

Seoul, 120-749
Seoul, 120-749

Tracking Information

NCT #
NCT02191644
Collaborators
Not Provided
Investigators
  • Principal Investigator: Jong Ho Lee, PhD Yonsei University
  • Jong Ho Lee, PhD Yonsei University