Recruitment

Recruitment Status
Completed

Inclusion Criteria

No history of periodontal therapy in preceding last 6 months
No use of antibiotics in the preceding 6 months
Systemically healthy subjects with probing depth (PD) ≥ 5 mm or periodontal attachment level (PAL) ≥ 4 to 6 mm and a radiographical vertical bone loss ≥ 3 mm
No history of periodontal therapy in preceding last 6 months
No use of antibiotics in the preceding 6 months
Systemically healthy subjects with probing depth (PD) ≥ 5 mm or periodontal attachment level (PAL) ≥ 4 to 6 mm and a radiographical vertical bone loss ≥ 3 mm

Exclusion Criteria

Subjects with aggressive periodontitis,
Pregnant or lactating females
Subjects with known systemic disease
...
Subjects with aggressive periodontitis,
Pregnant or lactating females
Subjects with known systemic disease
Immunocompromised subjects
Those on systemic ALN/bisphosphonate therapy
Alcoholics
Known or suspected allergy to the ALN/bisphosphonate group
Use of smokeless tobacco in any form,

Summary

Conditions
Chronic Periodontitis
Type
Interventional
Phase
Phase 2
Design
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Triple (Participant, Investigator, Outcomes Assessor)
  • Primary Purpose: Treatment

Participation Requirements

Age
Between 30 years and 50 years
Gender
Both males and females

Inclusion Criteria

No history of periodontal therapy in preceding last 6 months
No use of antibiotics in the preceding 6 months
Systemically healthy subjects with probing depth (PD) ≥ 5 mm or periodontal attachment level (PAL) ≥ 4 to 6 mm and a radiographical vertical bone loss ≥ 3 mm
No history of periodontal therapy in preceding last 6 months
No use of antibiotics in the preceding 6 months
Systemically healthy subjects with probing depth (PD) ≥ 5 mm or periodontal attachment level (PAL) ≥ 4 to 6 mm and a radiographical vertical bone loss ≥ 3 mm

Exclusion Criteria

Subjects with aggressive periodontitis,
Pregnant or lactating females
Subjects with known systemic disease
...
Subjects with aggressive periodontitis,
Pregnant or lactating females
Subjects with known systemic disease
Immunocompromised subjects
Those on systemic ALN/bisphosphonate therapy
Alcoholics
Known or suspected allergy to the ALN/bisphosphonate group
Use of smokeless tobacco in any form,

Tracking Information

NCT #
NCT02168543
Collaborators
Not Provided
Investigators
  • Principal Investigator: Dr. Anuj Sharma, BDS, MDS RIMS, Ranchi
  • Dr. Anuj Sharma, BDS, MDS RIMS, Ranchi