Recruitment

Recruitment Status
Completed
Estimated Enrollment
1000

Inclusion Criteria

Patients aged 18 years or older
Patients with a history of CRC without clear evidence of metastatic disease who have completed their acute cancer-specific treatment
Patients who have signed an approved informed consent form
Patients aged 18 years or older
Patients with a history of CRC without clear evidence of metastatic disease who have completed their acute cancer-specific treatment
Patients who have signed an approved informed consent form

Exclusion Criteria

Patients who are pregnant
Patients with a diverting ileostomy, with a history of inflammatory bowel disease, FAP, or active GI symptoms (gastrointestinal bleed, diarrhea, severe abdominal pain, etc.)
Patients who are pregnant
Patients with a diverting ileostomy, with a history of inflammatory bowel disease, FAP, or active GI symptoms (gastrointestinal bleed, diarrhea, severe abdominal pain, etc.)

Summary

Conditions
Colorectal Cancer
Type
Observational
Design
  • Observational Model: Case-Only
  • Time Perspective: Prospective

Participation Requirements

Age
Between 18 years and 125 years
Gender
Both males and females

Description

The goal of this study is to compare, both clinically and from a cost-effectiveness perspective, virtual or CT-C (CT-Colonography) to standard CT scan and optical colonoscopy (OC). Virtual colonoscopy is a combination of a radiologic evaluation of the abdomen and pelvis with intra-colonic imaging. P...

The goal of this study is to compare, both clinically and from a cost-effectiveness perspective, virtual or CT-C (CT-Colonography) to standard CT scan and optical colonoscopy (OC). Virtual colonoscopy is a combination of a radiologic evaluation of the abdomen and pelvis with intra-colonic imaging. Previous research supports the concept that CT-C may be an effective substitute for the current OC and address limited compliance for surveillance for CRC survivors. Post-operative CRC surveillance strategies are effective, but depend upon patient compliance which is less than desired. Improved adherence is linked with greater cost-effectiveness as well as better clinical outcomes. CT-C possesses potential advantages: convenience as a single test, less risk, possibly patient preference and lower total costs. Costs would be reduced through direct (provision of fewer optical colonoscopies) and indirect means (reduction in time lost from work by patient and chaperone, etc.). When extrapolated across the roughly 200,000 OCs performed annually in the US for this indication reduced utilization of even 50% in a high unit cost procedure like OC would yield substantial savings without a reduction in clinical quality.

Inclusion Criteria

Patients aged 18 years or older
Patients with a history of CRC without clear evidence of metastatic disease who have completed their acute cancer-specific treatment
Patients who have signed an approved informed consent form
Patients aged 18 years or older
Patients with a history of CRC without clear evidence of metastatic disease who have completed their acute cancer-specific treatment
Patients who have signed an approved informed consent form

Exclusion Criteria

Patients who are pregnant
Patients with a diverting ileostomy, with a history of inflammatory bowel disease, FAP, or active GI symptoms (gastrointestinal bleed, diarrhea, severe abdominal pain, etc.)
Patients who are pregnant
Patients with a diverting ileostomy, with a history of inflammatory bowel disease, FAP, or active GI symptoms (gastrointestinal bleed, diarrhea, severe abdominal pain, etc.)

Locations

Madison, Wisconsin, 53792
Chicago, Illinois, 60637
New York, New York, 10065
Philadelphia, Pennsylvania, 19111
Rochester, Minnesota, 55905
...
Madison, Wisconsin, 53792
Chicago, Illinois, 60637
New York, New York, 10065
Philadelphia, Pennsylvania, 19111
Rochester, Minnesota, 55905

Tracking Information

NCT #
NCT02143115
Collaborators
Not Provided
Investigators
  • Principal Investigator: David S Weinberg, MD Fox Chase Cancer Center
  • David S Weinberg, MD Fox Chase Cancer Center
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