The Study About the Efficacy of Oral Limaprost After Surgery for Cervical Myelopathy
Last updated on April 2022Recruitment
- Recruitment Status
- Recruiting
Inclusion Criteria
- Plan to undergo cervical surgery for myelopathy
- Signed informed consent of patient or legal guardian
- Compressive cervical myelopathy, confirmed by MRI, including C1-C2 instability, ossification of posterior longitudinal ligament
- ...
- Plan to undergo cervical surgery for myelopathy
- Signed informed consent of patient or legal guardian
- Compressive cervical myelopathy, confirmed by MRI, including C1-C2 instability, ossification of posterior longitudinal ligament
- JOA score less than 15 points
- Older than 20 years old
Exclusion Criteria
- Taking Limaprost before surgery
- Pregnancy or expected to be pregnant or breast feeding
- Infection or malignancy
- ...
- Taking Limaprost before surgery
- Pregnancy or expected to be pregnant or breast feeding
- Infection or malignancy
- severe cardiovascular, pulmonary, renal disease or distress, brain pathology
- patient cannot follow study protocol, for any reason
- any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study
- any related coagulopathy
- any drug to cause bleeding tendency
- severe pain from other disease
Summary
- Conditions
- Cervical Myelopathy
- Type
- Interventional
- Phase
- Phase 3
- Design
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
Participation Requirements
- Age
- Between 20 years and 125 years
- Gender
- Both males and females
Inclusion Criteria
- Plan to undergo cervical surgery for myelopathy
- Signed informed consent of patient or legal guardian
- Compressive cervical myelopathy, confirmed by MRI, including C1-C2 instability, ossification of posterior longitudinal ligament
- ...
- Plan to undergo cervical surgery for myelopathy
- Signed informed consent of patient or legal guardian
- Compressive cervical myelopathy, confirmed by MRI, including C1-C2 instability, ossification of posterior longitudinal ligament
- JOA score less than 15 points
- Older than 20 years old
Exclusion Criteria
- Taking Limaprost before surgery
- Pregnancy or expected to be pregnant or breast feeding
- Infection or malignancy
- ...
- Taking Limaprost before surgery
- Pregnancy or expected to be pregnant or breast feeding
- Infection or malignancy
- severe cardiovascular, pulmonary, renal disease or distress, brain pathology
- patient cannot follow study protocol, for any reason
- any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study
- any related coagulopathy
- any drug to cause bleeding tendency
- severe pain from other disease
Tracking Information
- NCT #
- NCT02125981
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Jin S. Yeom Seoul National University Bundang Hospital
- Jin S. Yeom Seoul National University Bundang Hospital
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