The Study About the Efficacy of Oral Limaprost After Surgery for Cervical Myelopathy
Last updated on September 2021Recruitment
- Recruitment Status
- Recruiting
Inclusion Criteria
- Compressive cervical myelopathy, confirmed by MRI, including C1-C2 instability, ossification of posterior longitudinal ligament
- Older than 20 years old
- JOA score less than 15 points
- ...
- Compressive cervical myelopathy, confirmed by MRI, including C1-C2 instability, ossification of posterior longitudinal ligament
- Older than 20 years old
- JOA score less than 15 points
- Plan to undergo cervical surgery for myelopathy
- Signed informed consent of patient or legal guardian
Exclusion Criteria
- any drug to cause bleeding tendency
- any related coagulopathy
- any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study
- ...
- any drug to cause bleeding tendency
- any related coagulopathy
- any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study
- patient cannot follow study protocol, for any reason
- Pregnancy or expected to be pregnant or breast feeding
- severe pain from other disease
- Taking Limaprost before surgery
- Infection or malignancy
- severe cardiovascular, pulmonary, renal disease or distress, brain pathology
Summary
- Conditions
- Cervical Myelopathy
- Type
- Interventional
- Phase
- Phase 3
- Design
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
Participation Requirements
- Age
- Between 20 years and 125 years
- Gender
- Both males and females
Inclusion Criteria
- Compressive cervical myelopathy, confirmed by MRI, including C1-C2 instability, ossification of posterior longitudinal ligament
- Older than 20 years old
- JOA score less than 15 points
- ...
- Compressive cervical myelopathy, confirmed by MRI, including C1-C2 instability, ossification of posterior longitudinal ligament
- Older than 20 years old
- JOA score less than 15 points
- Plan to undergo cervical surgery for myelopathy
- Signed informed consent of patient or legal guardian
Exclusion Criteria
- any drug to cause bleeding tendency
- any related coagulopathy
- any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study
- ...
- any drug to cause bleeding tendency
- any related coagulopathy
- any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study
- patient cannot follow study protocol, for any reason
- Pregnancy or expected to be pregnant or breast feeding
- severe pain from other disease
- Taking Limaprost before surgery
- Infection or malignancy
- severe cardiovascular, pulmonary, renal disease or distress, brain pathology
Locations
- Seongnam-si, Gyeonggi-do, 463-707
- Seongnam-si, Gyeonggi-do, 463-707
Tracking Information
- NCT #
- NCT02125981
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Jin S. Yeom Seoul National University Bundang Hospital
- Jin S. Yeom Seoul National University Bundang Hospital
Get Well Soon