The Study About the Efficacy of Oral Limaprost After Surgery for Cervical Myelopathy
Last updated on April 2022Recruitment
- Recruitment Status
- Recruiting
Inclusion Criteria
- Signed informed consent of patient or legal guardian
- Plan to undergo cervical surgery for myelopathy
- JOA score less than 15 points
- ...
- Signed informed consent of patient or legal guardian
- Plan to undergo cervical surgery for myelopathy
- JOA score less than 15 points
- Compressive cervical myelopathy, confirmed by MRI, including C1-C2 instability, ossification of posterior longitudinal ligament
- Older than 20 years old
Exclusion Criteria
- patient cannot follow study protocol, for any reason
- severe cardiovascular, pulmonary, renal disease or distress, brain pathology
- Taking Limaprost before surgery
- ...
- patient cannot follow study protocol, for any reason
- severe cardiovascular, pulmonary, renal disease or distress, brain pathology
- Taking Limaprost before surgery
- any related coagulopathy
- Infection or malignancy
- Pregnancy or expected to be pregnant or breast feeding
- any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study
- any drug to cause bleeding tendency
- severe pain from other disease
Summary
- Conditions
- Cervical Myelopathy
- Type
- Interventional
- Phase
- Phase 3
- Design
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
Participation Requirements
- Age
- Between 20 years and 125 years
- Gender
- Both males and females
Inclusion Criteria
- Signed informed consent of patient or legal guardian
- Plan to undergo cervical surgery for myelopathy
- JOA score less than 15 points
- ...
- Signed informed consent of patient or legal guardian
- Plan to undergo cervical surgery for myelopathy
- JOA score less than 15 points
- Compressive cervical myelopathy, confirmed by MRI, including C1-C2 instability, ossification of posterior longitudinal ligament
- Older than 20 years old
Exclusion Criteria
- patient cannot follow study protocol, for any reason
- severe cardiovascular, pulmonary, renal disease or distress, brain pathology
- Taking Limaprost before surgery
- ...
- patient cannot follow study protocol, for any reason
- severe cardiovascular, pulmonary, renal disease or distress, brain pathology
- Taking Limaprost before surgery
- any related coagulopathy
- Infection or malignancy
- Pregnancy or expected to be pregnant or breast feeding
- any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study
- any drug to cause bleeding tendency
- severe pain from other disease
Tracking Information
- NCT #
- NCT02125981
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Jin S. Yeom Seoul National University Bundang Hospital
- Jin S. Yeom Seoul National University Bundang Hospital
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