Recruitment

Recruitment Status
Completed
Estimated Enrollment
80

Inclusion Criterias

age over 20 y/o, less than 70 y/o
scheduled to receive VATS operations with OLV
age over 20 y/o, less than 70 y/o
scheduled to receive VATS operations with OLV

Exclusion Criterias

pulmonary disease
previous thoracic surgery
cardiac disease ( including arrhythmias, congestive heart failure, coronary cardiac disease, etc.)
pulmonary disease
previous thoracic surgery
cardiac disease ( including arrhythmias, congestive heart failure, coronary cardiac disease, etc.)

Summary

Conditions
Lung Neoplasms
Type
Observational
Design
  • Observational Model: Cohort
  • Time Perspective: Prospective

Participation Requirements

Age
Between 20 years and 70 years
Gender
Both males and females

Description

Non-intubated vedio-assisted thoracoscopic (VATS) is proved safely performed as well as traditional intubated VATS. However, the differences of hemodynamic changes and fluid responsiveness during one lung ventilation(OLV) between these two groups were rarely reported. For complete lung collapse, spo...

Non-intubated vedio-assisted thoracoscopic (VATS) is proved safely performed as well as traditional intubated VATS. However, the differences of hemodynamic changes and fluid responsiveness during one lung ventilation(OLV) between these two groups were rarely reported. For complete lung collapse, spontaneous negative pressure respiration must be well maintained on non-intubated VATS. In comparison, positive pressure ventilation on dependent lung was applied during OLV in intubated VATS. This study planned to compared the changes of hemodynamics (including blood pressure, heart rate, cardiac output) during OLV between groups. As functional hemodynamic monitoring (FloTrac system) was mostly utilized with positive pressure ventilation, the applicability of FloTrac in non- intubated VATS was also testified. In this study, we also measure the fluid responsiveness by FloTrac system with rapid infusion (within 10 minutes) of 10 mL/kg crystalloid fluid. We planned to compare the changes on cardiac output and the fluid responsiveness during OLV between these two groups.

Inclusion Criterias

age over 20 y/o, less than 70 y/o
scheduled to receive VATS operations with OLV
age over 20 y/o, less than 70 y/o
scheduled to receive VATS operations with OLV

Exclusion Criterias

pulmonary disease
previous thoracic surgery
cardiac disease ( including arrhythmias, congestive heart failure, coronary cardiac disease, etc.)
pulmonary disease
previous thoracic surgery
cardiac disease ( including arrhythmias, congestive heart failure, coronary cardiac disease, etc.)

Locations

Taipei, 100
Taipei, 100

Tracking Information

NCT #
NCT02123173
Collaborators
Not Provided
Investigators
  • Principal Investigator: Ya-Jung Cheng department of anesthesiology, national taiwan university hospital
  • Ya-Jung Cheng department of anesthesiology, national taiwan university hospital