Recruitment

Recruitment Status
Withdrawn
Estimated Enrollment
200

Exclusion Criteria

Pregnant women.
Patients with history of lymphoma or malignancy.
Pregnant women.
Patients with history of lymphoma or malignancy.

Summary

Conditions
  • Autoimmune Diseases
  • Dry Eyes
  • Dry Mouth
  • Sjogren's Syndrome
Type
Observational
Design
  • Observational Model: Cohort
  • Time Perspective: Prospective

Participation Requirements

Age
Between 9 years and 21 years
Gender
Both males and females

Description

Blood from patient and healthy controls will be collected once every 3-6 months. White blood cells from blood samples will be separated. Tests will be done to see which substances these cells make. Using sequencing techniques, the investigators will determine the genetic code of the receptors expres...

Blood from patient and healthy controls will be collected once every 3-6 months. White blood cells from blood samples will be separated. Tests will be done to see which substances these cells make. Using sequencing techniques, the investigators will determine the genetic code of the receptors expressed on these cells. The investigators plan to test how these cells change over the period of at least 3 years at different visits. In addition, the investigators will check how these changes relate to patients' general medical history relevant to autoimmune disease, lab results and physical examinations and exams pertinent to the diagnosis of autoimmune disease, and psychosocial data.

Exclusion Criteria

Pregnant women.
Patients with history of lymphoma or malignancy.
Pregnant women.
Patients with history of lymphoma or malignancy.

Tracking Information

NCT #
NCT02123147
Collaborators
Not Provided
Investigators
  • Principal Investigator: Cuong Nguyen, PhD University of Florida
  • Cuong Nguyen, PhD University of Florida