Recruitment

Recruitment Status
Completed

Inclusion Criteria

All patients(age≧18y)
Admitted for septic shock were considered eligible if they had no life-threatening systemic disease (ASA groups 1~3)
All patients(age≧18y)
Admitted for septic shock were considered eligible if they had no life-threatening systemic disease (ASA groups 1~3)

Exclusion Criteria

Disseminated cancer
Lactation
Secondary cancers
...
Disseminated cancer
Lactation
Secondary cancers
Mental disorders
Inflammatory bowel disease, or diseases hindering epidural analgesia

Summary

Conditions
  • Coagulation Dysfunction in Septic Shock
  • Hemodynamic Improvement Induced by Hydrocortisone
Type
Interventional
Phase
Phase 3
Design
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
  • Primary Purpose: Treatment

Participation Requirements

Age
Between 18 years and 78 years
Gender
Both males and females

Description

Patients were randomized to receive either low-dose hydrocortisone or matching placebo.Severity of coagulopathy was estimated using ISTH DIC score. We determined the complications and mortality in two groups, and analyzed the relationship between hydrocortisone and coagulopathy.

Patients were randomized to receive either low-dose hydrocortisone or matching placebo.Severity of coagulopathy was estimated using ISTH DIC score. We determined the complications and mortality in two groups, and analyzed the relationship between hydrocortisone and coagulopathy.

Inclusion Criteria

All patients(age≧18y)
Admitted for septic shock were considered eligible if they had no life-threatening systemic disease (ASA groups 1~3)
All patients(age≧18y)
Admitted for septic shock were considered eligible if they had no life-threatening systemic disease (ASA groups 1~3)

Exclusion Criteria

Disseminated cancer
Lactation
Secondary cancers
...
Disseminated cancer
Lactation
Secondary cancers
Mental disorders
Inflammatory bowel disease, or diseases hindering epidural analgesia

Tracking Information

NCT #
NCT02114710
Collaborators
Not Provided
Investigators
Not Provided