Recruitment

Recruitment Status
Completed
Estimated Enrollment
150

Summary

Conditions
Polycystic Ovary Syndrome
Type
Interventional
Phase
Phase 1
Design
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: None (Open Label)
  • Primary Purpose: Basic Science

Participation Requirements

Min Age
18
Max Age
50
Gender
Female

Description

The investigators propose to use both targeted and non-targeted metabolomic approaches to identify pathways associated with metformin's effect on insulin sensitivity, weight, androgens and endothelial function. This project will be the foundation for developing tailored therapeutic approaches to Pol...

The investigators propose to use both targeted and non-targeted metabolomic approaches to identify pathways associated with metformin's effect on insulin sensitivity, weight, androgens and endothelial function. This project will be the foundation for developing tailored therapeutic approaches to Polycystic Ovary Syndrome and identifying novel drug targets. This pilot project is intended to inform the development of hypothesis and specific aims for a future grant application to National Institutes of Health (NIH).

Locations

Rochester, Minnesota, 55905
Rochester, Minnesota, 55905

Tracking Information

NCT #
NCT02086526
Collaborators
Abbott Medical Devices
Investigators
  • Principal Investigator: Alice Chang, MD Mayo Clinic
  • Alice Chang, MD Mayo Clinic