Recruitment

Recruitment Status
Completed
Estimated Enrollment
50

Inclusion Criteria

Willing to be medication and supplement free 2 weeks prior to beginning study, and throughout the study. All forms of birth control are okay.
Healthy volunteers 25 to 55 years old.
Volunteers have a Body Mass Index (BMI), calculated from the ratio of height and weight, within a range of 18.5 to 35.
Willing to be medication and supplement free 2 weeks prior to beginning study, and throughout the study. All forms of birth control are okay.
Healthy volunteers 25 to 55 years old.
Volunteers have a Body Mass Index (BMI), calculated from the ratio of height and weight, within a range of 18.5 to 35.

Exclusion Criteria

Individuals unwilling or unable to comply with the study protocol (e.g. unable to remain medication or supplement free during the study).
Nicotine dependence
Alcohol dependence
...
Individuals unwilling or unable to comply with the study protocol (e.g. unable to remain medication or supplement free during the study).
Nicotine dependence
Alcohol dependence
Individuals unwilling or unable to take bupropion or have an allergy to bupropion
Any medical or surgical conditions which might significantly alter bupropion absorption (e.g., history of malabsorption, liver disease, gastric bypass surgery )
Pregnant or nursing women
Individuals with a history of psychiatric or neurological illness, including seizure disorders

Summary

Conditions
Depression
Type
Interventional
Phase
Phase 4
Design
  • Allocation: Randomized
  • Intervention Model: Crossover Assignment
  • Masking: Single (Outcomes Assessor)
  • Primary Purpose: Basic Science

Participation Requirements

Age
Between 25 years and 55 years
Gender
Both males and females

Inclusion Criteria

Willing to be medication and supplement free 2 weeks prior to beginning study, and throughout the study. All forms of birth control are okay.
Healthy volunteers 25 to 55 years old.
Volunteers have a Body Mass Index (BMI), calculated from the ratio of height and weight, within a range of 18.5 to 35.
Willing to be medication and supplement free 2 weeks prior to beginning study, and throughout the study. All forms of birth control are okay.
Healthy volunteers 25 to 55 years old.
Volunteers have a Body Mass Index (BMI), calculated from the ratio of height and weight, within a range of 18.5 to 35.

Exclusion Criteria

Individuals unwilling or unable to comply with the study protocol (e.g. unable to remain medication or supplement free during the study).
Nicotine dependence
Alcohol dependence
...
Individuals unwilling or unable to comply with the study protocol (e.g. unable to remain medication or supplement free during the study).
Nicotine dependence
Alcohol dependence
Individuals unwilling or unable to take bupropion or have an allergy to bupropion
Any medical or surgical conditions which might significantly alter bupropion absorption (e.g., history of malabsorption, liver disease, gastric bypass surgery )
Pregnant or nursing women
Individuals with a history of psychiatric or neurological illness, including seizure disorders

Tracking Information

NCT #
NCT02078180
Collaborators
Not Provided
Investigators
  • Principal Investigator: Duxin Sun, PhD University of Michigan
  • Duxin Sun, PhD University of Michigan