Pharmacokinetic Study of Bupropion Hydrochloride Products With Different Release Patterns
Last updated on April 2022Recruitment
- Recruitment Status
- Completed
- Estimated Enrollment
- 50
Inclusion Criteria
- Healthy volunteers 25 to 55 years old.
- Willing to be medication and supplement free 2 weeks prior to beginning study, and throughout the study. All forms of birth control are okay.
- Volunteers have a Body Mass Index (BMI), calculated from the ratio of height and weight, within a range of 18.5 to 35.
- Healthy volunteers 25 to 55 years old.
- Willing to be medication and supplement free 2 weeks prior to beginning study, and throughout the study. All forms of birth control are okay.
- Volunteers have a Body Mass Index (BMI), calculated from the ratio of height and weight, within a range of 18.5 to 35.
Exclusion Criteria
- Individuals with a history of psychiatric or neurological illness, including seizure disorders
- Individuals unwilling or unable to take bupropion or have an allergy to bupropion
- Nicotine dependence
- ...
- Individuals with a history of psychiatric or neurological illness, including seizure disorders
- Individuals unwilling or unable to take bupropion or have an allergy to bupropion
- Nicotine dependence
- Any medical or surgical conditions which might significantly alter bupropion absorption (e.g., history of malabsorption, liver disease, gastric bypass surgery )
- Pregnant or nursing women
- Individuals unwilling or unable to comply with the study protocol (e.g. unable to remain medication or supplement free during the study).
- Alcohol dependence
Summary
- Conditions
- Depression
- Type
- Interventional
- Phase
- Phase 4
- Design
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Basic Science
Participation Requirements
- Age
- Between 25 years and 55 years
- Gender
- Both males and females
Inclusion Criteria
- Healthy volunteers 25 to 55 years old.
- Willing to be medication and supplement free 2 weeks prior to beginning study, and throughout the study. All forms of birth control are okay.
- Volunteers have a Body Mass Index (BMI), calculated from the ratio of height and weight, within a range of 18.5 to 35.
- Healthy volunteers 25 to 55 years old.
- Willing to be medication and supplement free 2 weeks prior to beginning study, and throughout the study. All forms of birth control are okay.
- Volunteers have a Body Mass Index (BMI), calculated from the ratio of height and weight, within a range of 18.5 to 35.
Exclusion Criteria
- Individuals with a history of psychiatric or neurological illness, including seizure disorders
- Individuals unwilling or unable to take bupropion or have an allergy to bupropion
- Nicotine dependence
- ...
- Individuals with a history of psychiatric or neurological illness, including seizure disorders
- Individuals unwilling or unable to take bupropion or have an allergy to bupropion
- Nicotine dependence
- Any medical or surgical conditions which might significantly alter bupropion absorption (e.g., history of malabsorption, liver disease, gastric bypass surgery )
- Pregnant or nursing women
- Individuals unwilling or unable to comply with the study protocol (e.g. unable to remain medication or supplement free during the study).
- Alcohol dependence
Tracking Information
- NCT #
- NCT02078180
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Duxin Sun, PhD University of Michigan
- Duxin Sun, PhD University of Michigan
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