Measurement of D-Dimer Levels in Patients With Confirmed Deep Vein Thrombosis
Last updated on April 2022Recruitment
- Recruitment Status
- Terminated
- Estimated Enrollment
- 25
Inclusion Criteria
- Patient is < 80 years old.
- Patient presenting at least one of these symptoms indicative of proximal DVT: leg pain, tenderness (discomfort through palpation), leg swelling and /or edema,
- Low or moderate Wells score
- ...
- Patient is < 80 years old.
- Patient presenting at least one of these symptoms indicative of proximal DVT: leg pain, tenderness (discomfort through palpation), leg swelling and /or edema,
- Low or moderate Wells score
- Patient has confirmed proximal DVT by imaging
- The study population tested will be recruited from ambulatory outpatients (presenting at the emergency unit or outpatient clinic) suspected of having DVT.
- Patient provides written informed consent to participate in the sample collection
Exclusion Criteria
- Atherosclerotic vascular disease thrombosis within the previous 1month (e.g. myocardial infarction, stroke, coronary syndrome, peripheral artery disease stage III or IV),
- Patients presenting with a suspect thrombotic event related to catheter implantation
- Deep hematoma diagnosed by imaging techniques within the previous one (1) month,
- ...
- Atherosclerotic vascular disease thrombosis within the previous 1month (e.g. myocardial infarction, stroke, coronary syndrome, peripheral artery disease stage III or IV),
- Patients presenting with a suspect thrombotic event related to catheter implantation
- Deep hematoma diagnosed by imaging techniques within the previous one (1) month,
- Fibrinolytic therapy within the previous seven (7) days,
- Sickle cell disease,
- Bone fracture or surgery (with general anesthesia longer than thirty (30) minutes) within the previous one (1) month,
- Sepsis, severe infections, pneumonia within the previous 1 month,
- Disseminated malignancies and active cancer (active cancer defined as: cancer for which therapeutic or palliative treatment is either ongoing at the time of enrolment or has stopped less than six (6) months before enrolment),
- Ongoing therapeutic anticoagulants (curative and preventive treatment) starting twenty four (24) hours or more before the blood drawing for D-dimer testing
- Known liver cirrhosis,
- Pregnancy or post-partum within the previous 1 month,
Summary
- Conditions
- Deep Venous Thrombosis
- Type
- Observational
- Design
- Observational Model: Case-Only
- Time Perspective: Prospective
Participation Requirements
- Age
- Younger than 80 years
- Gender
- Both males and females
Inclusion Criteria
- Patient is < 80 years old.
- Patient presenting at least one of these symptoms indicative of proximal DVT: leg pain, tenderness (discomfort through palpation), leg swelling and /or edema,
- Low or moderate Wells score
- ...
- Patient is < 80 years old.
- Patient presenting at least one of these symptoms indicative of proximal DVT: leg pain, tenderness (discomfort through palpation), leg swelling and /or edema,
- Low or moderate Wells score
- Patient has confirmed proximal DVT by imaging
- The study population tested will be recruited from ambulatory outpatients (presenting at the emergency unit or outpatient clinic) suspected of having DVT.
- Patient provides written informed consent to participate in the sample collection
Exclusion Criteria
- Atherosclerotic vascular disease thrombosis within the previous 1month (e.g. myocardial infarction, stroke, coronary syndrome, peripheral artery disease stage III or IV),
- Patients presenting with a suspect thrombotic event related to catheter implantation
- Deep hematoma diagnosed by imaging techniques within the previous one (1) month,
- ...
- Atherosclerotic vascular disease thrombosis within the previous 1month (e.g. myocardial infarction, stroke, coronary syndrome, peripheral artery disease stage III or IV),
- Patients presenting with a suspect thrombotic event related to catheter implantation
- Deep hematoma diagnosed by imaging techniques within the previous one (1) month,
- Fibrinolytic therapy within the previous seven (7) days,
- Sickle cell disease,
- Bone fracture or surgery (with general anesthesia longer than thirty (30) minutes) within the previous one (1) month,
- Sepsis, severe infections, pneumonia within the previous 1 month,
- Disseminated malignancies and active cancer (active cancer defined as: cancer for which therapeutic or palliative treatment is either ongoing at the time of enrolment or has stopped less than six (6) months before enrolment),
- Ongoing therapeutic anticoagulants (curative and preventive treatment) starting twenty four (24) hours or more before the blood drawing for D-dimer testing
- Known liver cirrhosis,
- Pregnancy or post-partum within the previous 1 month,
Tracking Information
- NCT #
- NCT02078154
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Suman Wasan Rathbun, MD University of Oklahoma Health Sciences
- Suman Wasan Rathbun, MD University of Oklahoma Health Sciences