Recruitment

Recruitment Status
Unknown status
Estimated Enrollment
25

Inclusion Criteria

DCM diagnosed for more than two weeks without new ventricular arrhythmias or AuriculoVentricular Block (AVB) second or third degree , who responded to the usual treatment in the first two weeks of treatment
No family history of DCM
Patients who have read and understood the information letter and who signed the consent form
...
DCM diagnosed for more than two weeks without new ventricular arrhythmias or AuriculoVentricular Block (AVB) second or third degree , who responded to the usual treatment in the first two weeks of treatment
No family history of DCM
Patients who have read and understood the information letter and who signed the consent form
Absence of other causes of non-family DCM discovered during the initial etiological ( some deficiency , toxic alcoholic or drug )
Patients with DCM as defined by the European Society of Cardiology and recognized as such by the clinician cardiologist
Lake of clinical or biological cases for periphiral myopathy or myotonia
Affiliated to a social insurance
Patients who underwent cardiac MRI for etiological DCM for less than four weeks at the time of obtaining consent
Patients above 18 years of age

Exclusion Criteria

No affiliation to a social insurance
Patient with signs of circulatory failure or congestive heart failure requiring intravenous positive inotropic therapy or diuretic therapy
Patients with connective : rheumatoid arthritis , systemic lupus erythematosus , systemic sclerosis , dermato- polymyositis , mixed connective
...
No affiliation to a social insurance
Patient with signs of circulatory failure or congestive heart failure requiring intravenous positive inotropic therapy or diuretic therapy
Patients with connective : rheumatoid arthritis , systemic lupus erythematosus , systemic sclerosis , dermato- polymyositis , mixed connective
Patients with active neoplasia
Hypersensitivity to heparin.
Pregnant or lactating women
Patients with chronic liver disease
Treatment immunosuppressive received from cardiac MRI
Minors
History of severe thrombocytopenia type II ( heparin induced thrombocytopenia or immuno- allergic thrombocytopenia ) , heparin or unfractionated heparin , low molecular weight
History of chemotherapy with anthracyclines
Family history of DCM
Eosinophilia or immuno- allergic mechanism suspected
Significant organic valvular echocardiography
Ischemic cardiomyopathy defined by history of myocardial infarction or myocardial revascularization , stenosis ≥ 75% of the core or the left coronary artery anterior interventricular proximal stenosis ≥ 75% on at least two epicardial vessels
Patients with active tuberculosis
Other causes of non-family DCM discovered during the initial etiological ( some deficiency , toxic alcohol or medication , endocrine )
History of sarcoidosis
Patients with Crohn's disease
History of acute myocarditis
Major Trust

Summary

Conditions
Patients With Idiopathic Dilated Cardiomyopathy
Type
Interventional
Design
  • Allocation: N/A
  • Intervention Model: Single Group Assignment
  • Masking: None (Open Label)
  • Primary Purpose: Diagnostic

Participation Requirements

Age
Between 18 years and 125 years
Gender
Both males and females

Inclusion Criteria

DCM diagnosed for more than two weeks without new ventricular arrhythmias or AuriculoVentricular Block (AVB) second or third degree , who responded to the usual treatment in the first two weeks of treatment
No family history of DCM
Patients who have read and understood the information letter and who signed the consent form
...
DCM diagnosed for more than two weeks without new ventricular arrhythmias or AuriculoVentricular Block (AVB) second or third degree , who responded to the usual treatment in the first two weeks of treatment
No family history of DCM
Patients who have read and understood the information letter and who signed the consent form
Absence of other causes of non-family DCM discovered during the initial etiological ( some deficiency , toxic alcoholic or drug )
Patients with DCM as defined by the European Society of Cardiology and recognized as such by the clinician cardiologist
Lake of clinical or biological cases for periphiral myopathy or myotonia
Affiliated to a social insurance
Patients who underwent cardiac MRI for etiological DCM for less than four weeks at the time of obtaining consent
Patients above 18 years of age

Exclusion Criteria

No affiliation to a social insurance
Patient with signs of circulatory failure or congestive heart failure requiring intravenous positive inotropic therapy or diuretic therapy
Patients with connective : rheumatoid arthritis , systemic lupus erythematosus , systemic sclerosis , dermato- polymyositis , mixed connective
...
No affiliation to a social insurance
Patient with signs of circulatory failure or congestive heart failure requiring intravenous positive inotropic therapy or diuretic therapy
Patients with connective : rheumatoid arthritis , systemic lupus erythematosus , systemic sclerosis , dermato- polymyositis , mixed connective
Patients with active neoplasia
Hypersensitivity to heparin.
Pregnant or lactating women
Patients with chronic liver disease
Treatment immunosuppressive received from cardiac MRI
Minors
History of severe thrombocytopenia type II ( heparin induced thrombocytopenia or immuno- allergic thrombocytopenia ) , heparin or unfractionated heparin , low molecular weight
History of chemotherapy with anthracyclines
Family history of DCM
Eosinophilia or immuno- allergic mechanism suspected
Significant organic valvular echocardiography
Ischemic cardiomyopathy defined by history of myocardial infarction or myocardial revascularization , stenosis ≥ 75% of the core or the left coronary artery anterior interventricular proximal stenosis ≥ 75% on at least two epicardial vessels
Patients with active tuberculosis
Other causes of non-family DCM discovered during the initial etiological ( some deficiency , toxic alcohol or medication , endocrine )
History of sarcoidosis
Patients with Crohn's disease
History of acute myocarditis
Major Trust

Tracking Information

NCT #
NCT02078141
Collaborators
Not Provided
Investigators
  • Principal Investigator: Nicolas Piriou, MD Nantes UH
  • Nicolas Piriou, MD Nantes UH
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