Recruitment

Recruitment Status
Completed
Estimated Enrollment
20

Inclusion Criterias

patients who failed to achieve a decline of 2 log HCV RNA IU/ml after 12 weeks of treatment
who never achieved undetectable HCV RNA during treatment of a minimum duration of 24 weeks
patients who failed to achieve a decline of 2 log HCV RNA IU/ml after 12 weeks of treatment
who never achieved undetectable HCV RNA during treatment of a minimum duration of 24 weeks

Exclusion Criterias

presence of decompensate cirrhosis
Receiving anti neoplasm, anti viral or immunomedulator drugs during 6 months prior to study
coinfection with Hepatitis A,C,D viruses or HIV
...
presence of decompensate cirrhosis
Receiving anti neoplasm, anti viral or immunomedulator drugs during 6 months prior to study
coinfection with Hepatitis A,C,D viruses or HIV
active Alcohol user
refusing to give informed consent
pregnancy
Severe dysfunction of liver and kidney
breast feeding

Summary

Conditions
Hepatitis C Virus
Type
Interventional
Phase
Phase 4
Design
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
  • Primary Purpose: Treatment

Participation Requirements

Age
Between 18 years and 60 years
Gender
Both males and females

Inclusion Criterias

patients who failed to achieve a decline of 2 log HCV RNA IU/ml after 12 weeks of treatment
who never achieved undetectable HCV RNA during treatment of a minimum duration of 24 weeks
patients who failed to achieve a decline of 2 log HCV RNA IU/ml after 12 weeks of treatment
who never achieved undetectable HCV RNA during treatment of a minimum duration of 24 weeks

Exclusion Criterias

presence of decompensate cirrhosis
Receiving anti neoplasm, anti viral or immunomedulator drugs during 6 months prior to study
coinfection with Hepatitis A,C,D viruses or HIV
...
presence of decompensate cirrhosis
Receiving anti neoplasm, anti viral or immunomedulator drugs during 6 months prior to study
coinfection with Hepatitis A,C,D viruses or HIV
active Alcohol user
refusing to give informed consent
pregnancy
Severe dysfunction of liver and kidney
breast feeding

Locations

Shiraz, Fars
Shiraz, Fars

Tracking Information

NCT #
NCT02058173
Collaborators
Not Provided
Investigators
Study Chair: Kamran B Lankarani, M.D Health policy research center