Ultrasonographic Measurements of the Median Nerve Before and After Splinting for Carpal Tunnel Syndrome
Last updated on April 2022Recruitment
- Recruitment Status
- Completed
- Estimated Enrollment
- 350
Inclusion Criteria
- Control subjects without symptoms of carpal tunnel syndrome.
- 18 years or older and;
- Diagnosis of mild to moderate CTS with median motor latency at 8 cm is greater than 4.5 milliseconds or Combined Sensory Index > 0.9 where first line therapy is indicated to include nocturnal wrist bracing
- Control subjects without symptoms of carpal tunnel syndrome.
- 18 years or older and;
- Diagnosis of mild to moderate CTS with median motor latency at 8 cm is greater than 4.5 milliseconds or Combined Sensory Index > 0.9 where first line therapy is indicated to include nocturnal wrist bracing
Exclusion Criteria
- Diagnosed Severe CTS or Chronic symptoms of carpal tunnel, greater than 1 year, this includes wasting of the hand muscles
- History of electrodiagnostic evidence of generalized polyneuropathy or evidence of denervation
- Not fluent in English as NeuroQOL and other subjective information is limited to the English language interpretation
- ...
- Diagnosed Severe CTS or Chronic symptoms of carpal tunnel, greater than 1 year, this includes wasting of the hand muscles
- History of electrodiagnostic evidence of generalized polyneuropathy or evidence of denervation
- Not fluent in English as NeuroQOL and other subjective information is limited to the English language interpretation
- Untreated hypothyroidism, Rheumatologic disorders
- Diagnosed neuromuscular disorders which may complicate CTS diagnosis
- Implanted electronic device (pacemaker, intrathecal pump/stimulator)
- History of wrist, hand fracture or severe trauma to affected hand and/or wrist
- Any illness that makes it unsafe for the patient to participate in the study
- Known tumor, mass or deformity of the hand/wrist
- Inflammatory articular disease of the joints or tendons Existing cervical radiculopathy or previous surgeries to the neck for radicular symptoms
- Evidence of severe CTS as seen with electromyographic changes in the body of the muscle
- Undergoing or previously treated for carpal tunnel on affected side. This includes surgery (carpal tunnel release), corticosteroid injections, bracing within the last 3 months while wearing the brace consistently every night, or any other intervention.
- Currently pregnant or < 3 months post partum
Summary
- Conditions
- Carpal Tunnel Syndrome
- Type
- Observational
- Design
- Observational Model: Case-Control
- Time Perspective: Prospective
Participation Requirements
- Age
- Between 18 years and 125 years
- Gender
- Both males and females
Inclusion Criteria
- Control subjects without symptoms of carpal tunnel syndrome.
- 18 years or older and;
- Diagnosis of mild to moderate CTS with median motor latency at 8 cm is greater than 4.5 milliseconds or Combined Sensory Index > 0.9 where first line therapy is indicated to include nocturnal wrist bracing
- Control subjects without symptoms of carpal tunnel syndrome.
- 18 years or older and;
- Diagnosis of mild to moderate CTS with median motor latency at 8 cm is greater than 4.5 milliseconds or Combined Sensory Index > 0.9 where first line therapy is indicated to include nocturnal wrist bracing
Exclusion Criteria
- Diagnosed Severe CTS or Chronic symptoms of carpal tunnel, greater than 1 year, this includes wasting of the hand muscles
- History of electrodiagnostic evidence of generalized polyneuropathy or evidence of denervation
- Not fluent in English as NeuroQOL and other subjective information is limited to the English language interpretation
- ...
- Diagnosed Severe CTS or Chronic symptoms of carpal tunnel, greater than 1 year, this includes wasting of the hand muscles
- History of electrodiagnostic evidence of generalized polyneuropathy or evidence of denervation
- Not fluent in English as NeuroQOL and other subjective information is limited to the English language interpretation
- Untreated hypothyroidism, Rheumatologic disorders
- Diagnosed neuromuscular disorders which may complicate CTS diagnosis
- Implanted electronic device (pacemaker, intrathecal pump/stimulator)
- History of wrist, hand fracture or severe trauma to affected hand and/or wrist
- Any illness that makes it unsafe for the patient to participate in the study
- Known tumor, mass or deformity of the hand/wrist
- Inflammatory articular disease of the joints or tendons Existing cervical radiculopathy or previous surgeries to the neck for radicular symptoms
- Evidence of severe CTS as seen with electromyographic changes in the body of the muscle
- Undergoing or previously treated for carpal tunnel on affected side. This includes surgery (carpal tunnel release), corticosteroid injections, bracing within the last 3 months while wearing the brace consistently every night, or any other intervention.
- Currently pregnant or < 3 months post partum
Tracking Information
- NCT #
- NCT02038205
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Nanette Joyce, DO University of California, Davis
- Nanette Joyce, DO University of California, Davis
Get Well Soon