Recruitment

Recruitment Status
Recruiting

Inclusion Criteria

diabetic patients requiring intravitreal injection,cataract surgery or vitrectomy
nondiabetic patients asking cataract surgery or vitrectomy for posterior segment nonproliferative disorders.
age over 20 years
...
diabetic patients requiring intravitreal injection,cataract surgery or vitrectomy
nondiabetic patients asking cataract surgery or vitrectomy for posterior segment nonproliferative disorders.
age over 20 years
diabetic patients requiring opthalmologic treatments for different degrees of decreasing of visual acuity.

Exclusion Criteria

patients that received any anti-vascular endothelial growth factor agent for proliferative disease before taking sample of aqueous humor
patients with recent ocular trauma
under the age of 20 years
...
patients that received any anti-vascular endothelial growth factor agent for proliferative disease before taking sample of aqueous humor
patients with recent ocular trauma
under the age of 20 years
patients that did not signed the informed consent of the trial
patients with intraocular inflammations or infections that requiring any pharmaceutical agent

Summary

Conditions
Diabetic Retinopathy
Type
Observational
Design
  • Observational Model: Case-Control
  • Time Perspective: Prospective

Participation Requirements

Age
Between 20 years and 80 years
Gender
Both males and females

Description

This prospective, case-control study included 50 patients(50eyes) with severe nonproliferative diabetic retinopathy or proliferative diabetic retinopathy and 50 patient with nondiabetic retinopathy or cataract. Aqueous humor was taken before injection of anti-vascular endothelial growth factor agent...

This prospective, case-control study included 50 patients(50eyes) with severe nonproliferative diabetic retinopathy or proliferative diabetic retinopathy and 50 patient with nondiabetic retinopathy or cataract. Aqueous humor was taken before injection of anti-vascular endothelial growth factor agent or pars plana vitrectomy for other retinal disease. Angiogenic and non-angiogenic proteins were analyzed.

Inclusion Criteria

diabetic patients requiring intravitreal injection,cataract surgery or vitrectomy
nondiabetic patients asking cataract surgery or vitrectomy for posterior segment nonproliferative disorders.
age over 20 years
...
diabetic patients requiring intravitreal injection,cataract surgery or vitrectomy
nondiabetic patients asking cataract surgery or vitrectomy for posterior segment nonproliferative disorders.
age over 20 years
diabetic patients requiring opthalmologic treatments for different degrees of decreasing of visual acuity.

Exclusion Criteria

patients that received any anti-vascular endothelial growth factor agent for proliferative disease before taking sample of aqueous humor
patients with recent ocular trauma
under the age of 20 years
...
patients that received any anti-vascular endothelial growth factor agent for proliferative disease before taking sample of aqueous humor
patients with recent ocular trauma
under the age of 20 years
patients that did not signed the informed consent of the trial
patients with intraocular inflammations or infections that requiring any pharmaceutical agent

Tracking Information

NCT #
NCT02026843
Collaborators
Not Provided
Investigators
  • Principal Investigator: Dong Ho Park, M.D Kyungpook National University Hospital
  • Dong Ho Park, M.D Kyungpook National University Hospital
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