Comparison of the Effect of Ondansetron and Combined Ondansetron and Betahistine on Postoperative Nausea and Vomiting After Gynecological Laparoscopy
Last updated on April 2022Recruitment
- Recruitment Status
- Completed
Inclusion Criteria
- American society of Anesthesiologists physical class I, Ⅱ, between the ages of 20 and 70 years
- Patient scheduled for elective gynecological laparoscopic surgery
- American society of Anesthesiologists physical class I, Ⅱ, between the ages of 20 and 70 years
- Patient scheduled for elective gynecological laparoscopic surgery
Exclusion Criteria
- allergy to ondansetron or betahistine
- vomiting within 24h
- QT prolongation (QTc > 440ms)
- ...
- allergy to ondansetron or betahistine
- vomiting within 24h
- QT prolongation (QTc > 440ms)
- gastrointestinal disease
- Pheochromocytoma
- pregnant
- problem with communication
- administration of antiemetics or opioids within 24h
- BMI > 35 kg/m2
- hepatorenal disease
Summary
- Conditions
- Nausea and Vomiting
- Type
- Interventional
- Design
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Care Provider)
- Primary Purpose: Prevention
Participation Requirements
- Age
- Between 20 years and 70 years
- Gender
- Both males and females
Inclusion Criteria
- American society of Anesthesiologists physical class I, Ⅱ, between the ages of 20 and 70 years
- Patient scheduled for elective gynecological laparoscopic surgery
- American society of Anesthesiologists physical class I, Ⅱ, between the ages of 20 and 70 years
- Patient scheduled for elective gynecological laparoscopic surgery
Exclusion Criteria
- allergy to ondansetron or betahistine
- vomiting within 24h
- QT prolongation (QTc > 440ms)
- ...
- allergy to ondansetron or betahistine
- vomiting within 24h
- QT prolongation (QTc > 440ms)
- gastrointestinal disease
- Pheochromocytoma
- pregnant
- problem with communication
- administration of antiemetics or opioids within 24h
- BMI > 35 kg/m2
- hepatorenal disease
Tracking Information
- NCT #
- NCT02026778
- Collaborators
- Not Provided
- Investigators
- Not Provided
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