Recruitment

Recruitment Status
Completed

Inclusion Criteria

American society of Anesthesiologists physical class I, Ⅱ, between the ages of 20 and 70 years
Patient scheduled for elective gynecological laparoscopic surgery
American society of Anesthesiologists physical class I, Ⅱ, between the ages of 20 and 70 years
Patient scheduled for elective gynecological laparoscopic surgery

Exclusion Criteria

administration of antiemetics or opioids within 24h
allergy to ondansetron or betahistine
QT prolongation (QTc > 440ms)
...
administration of antiemetics or opioids within 24h
allergy to ondansetron or betahistine
QT prolongation (QTc > 440ms)
Pheochromocytoma
vomiting within 24h
hepatorenal disease
problem with communication
BMI > 35 kg/m2
pregnant
gastrointestinal disease

Summary

Conditions
Nausea and Vomiting
Type
Interventional
Design
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Double (Participant, Care Provider)
  • Primary Purpose: Prevention

Participation Requirements

Age
Between 20 years and 70 years
Gender
Both males and females

Inclusion Criteria

American society of Anesthesiologists physical class I, Ⅱ, between the ages of 20 and 70 years
Patient scheduled for elective gynecological laparoscopic surgery
American society of Anesthesiologists physical class I, Ⅱ, between the ages of 20 and 70 years
Patient scheduled for elective gynecological laparoscopic surgery

Exclusion Criteria

administration of antiemetics or opioids within 24h
allergy to ondansetron or betahistine
QT prolongation (QTc > 440ms)
...
administration of antiemetics or opioids within 24h
allergy to ondansetron or betahistine
QT prolongation (QTc > 440ms)
Pheochromocytoma
vomiting within 24h
hepatorenal disease
problem with communication
BMI > 35 kg/m2
pregnant
gastrointestinal disease

Tracking Information

NCT #
NCT02026778
Collaborators
Not Provided
Investigators
Not Provided