Comparison of the Effect of Ondansetron and Combined Ondansetron and Betahistine on Postoperative Nausea and Vomiting After Gynecological Laparoscopy
Last updated on April 2022Recruitment
- Recruitment Status
- Completed
Inclusion Criteria
- Patient scheduled for elective gynecological laparoscopic surgery
- American society of Anesthesiologists physical class I, Ⅱ, between the ages of 20 and 70 years
- Patient scheduled for elective gynecological laparoscopic surgery
- American society of Anesthesiologists physical class I, Ⅱ, between the ages of 20 and 70 years
Exclusion Criteria
- administration of antiemetics or opioids within 24h
- vomiting within 24h
- allergy to ondansetron or betahistine
- ...
- administration of antiemetics or opioids within 24h
- vomiting within 24h
- allergy to ondansetron or betahistine
- Pheochromocytoma
- problem with communication
- BMI > 35 kg/m2
- gastrointestinal disease
- hepatorenal disease
- pregnant
- QT prolongation (QTc > 440ms)
Summary
- Conditions
- Nausea and Vomiting
- Type
- Interventional
- Design
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Care Provider)
- Primary Purpose: Prevention
Participation Requirements
- Age
- Between 20 years and 70 years
- Gender
- Both males and females
Inclusion Criteria
- Patient scheduled for elective gynecological laparoscopic surgery
- American society of Anesthesiologists physical class I, Ⅱ, between the ages of 20 and 70 years
- Patient scheduled for elective gynecological laparoscopic surgery
- American society of Anesthesiologists physical class I, Ⅱ, between the ages of 20 and 70 years
Exclusion Criteria
- administration of antiemetics or opioids within 24h
- vomiting within 24h
- allergy to ondansetron or betahistine
- ...
- administration of antiemetics or opioids within 24h
- vomiting within 24h
- allergy to ondansetron or betahistine
- Pheochromocytoma
- problem with communication
- BMI > 35 kg/m2
- gastrointestinal disease
- hepatorenal disease
- pregnant
- QT prolongation (QTc > 440ms)
Tracking Information
- NCT #
- NCT02026778
- Collaborators
- Not Provided
- Investigators
- Not Provided
Get Well Soon