Recruitment

Recruitment Status
Recruiting
Estimated Enrollment
9999

Inclusion Criterias

Adult individuals (male and female) who have a personal diagnosis/history of cancer
Adult individuals who are able to speak English.
Adult individuals with no history of cancer for normal control registry.
...
Adult individuals (male and female) who have a personal diagnosis/history of cancer
Adult individuals who are able to speak English.
Adult individuals with no history of cancer for normal control registry.
19 years of age or older.
Able to provide consent.
Adult individuals who have a risk for developing cancer or suspicious clinical findings

Exclusion Criterias

Anyone who does not meet the above inclusion criteria for this project.
Non-English speaking individuals.
Individuals unable to provide informed consent by virtue of cognitive impairment.
...
Anyone who does not meet the above inclusion criteria for this project.
Non-English speaking individuals.
Individuals unable to provide informed consent by virtue of cognitive impairment.
Individuals under age 19.

Summary

Conditions
  • Bladder Cancer
  • Anal Cancer
  • Bile Duct Cancer
  • Unknown Primary Tumor
  • Small Intestine Cancer
  • Gallbladder Cancer
  • Gastric Cancer
  • Mesothelioma
  • Nasal Cavity Cancer
  • Breast Cancer
  • Lip Cancer
  • Thyroid Cancer
  • Multiple Myeloma
  • Urethral Cancer
  • Skin Cancer
  • GIST
  • Sarcoma
  • Peritoneal Surface Malignancies
  • Lung Cancer
  • Penile Cancer
  • Ureter Cancer
  • CNS Cancer
  • Oral Cavity Cancer
  • Pancreatic Cancer
  • Healthy Control
  • Lynch Syndrome
  • Oropharyngeal Cancer
  • Prostate Cancer
  • CNS Tumor
  • Colon Cancer
  • Testicular Cancer
  • Paranasal Sinus Cancer
  • Plasma Cell Dyscrasia
  • Duodenal Cancer
  • Endometrial Cancer
  • Esophageal Cancer
  • Rectal Cancer
  • Liver Cancer
  • Thymus Cancer
  • Vaginal Cancer
  • Ovarian Cancer
  • Melanoma
  • Hypopharyngeal Cancer
  • Kidney Cancer
  • Nasopharyngeal Cancer
  • Neuroendocrine Tumors
  • Laryngeal Cancer
  • Salivary Gland Cancer
  • Leukemia
  • Familial Adenomatous Polyposis
Design
  • Observational Model: Cohort
  • Time Perspective: Prospective

Participation Requirements

Age
Between 19 years and 110 years
Gender
Both males and females

Description

The integrated Cancer Repository for Cancer Research (iCaRe2 http://icare2project.org) is a unique sociotechnical resource for the collection and management of cancer and health-related data at the Fred & Pamela Buffett Cancer Center at University of Nebraska Medical Center (UNMC). The iCaRe2 is a m...

The integrated Cancer Repository for Cancer Research (iCaRe2 http://icare2project.org) is a unique sociotechnical resource for the collection and management of cancer and health-related data at the Fred & Pamela Buffett Cancer Center at University of Nebraska Medical Center (UNMC). The iCaRe2 is a multi-center, semantically-interoperable and easily-customizable cancer data resource which is aimed at collecting, managing, mining and sharing the comprehensive, multi-dimensional cancer-related data on cancer patients and biospecimens (such as tumor specimens, germ line DNA, serum, urine, and plasma) collected from those individuals. The iCaRe2 provides: (i) a HIPAA compliant, secure, efficient and user-friendly mechanism for data and validation; (ii) utilization of standard vocabulary and data elements; and (iii) the ad-hoc data reporting capabilities. The iCaRe2 serves as a collaboration platform for studies (including clinical trials) performed in centers with expertise in cancer biology, pathology, epidemiology, genetics, early detection, and patient care. The iCaRe2 has been developed as an expansion of the biocomputing framework that initially included four multi-center collaborative registries: (i) the PCCR (Pancreatic Cancer Collaborative Registry that was established in 2001), (ii) the BCCR (Breast Cancer Collaborative Registry - established in 2006 ); (iii) the TCCR (Thyroid Cancer Collaborative Registry - established in 2006), and (iv) the GPHID (Great Plains Health Informatics Database - established in 2011 to enroll subjects who have no personal history of cancer diagnosis at the time of enrollment). At present, this framework has been incrementally expanded to include the Thoracic Oncology Collaborative Registry (TOCR), GenitoUrinary Cancer Collaborative Registry (GUCARE), Head and Neck Cancer Collaborative Registry (HNCCR), Gastrointestinal & Abdominal Cavity Cancer Collaborative Registry (GACCaRe), Central Nervous System Tumor Collaborative Registry (CTCR), Leukemia and Myeloid Neoplasm Registry (LEMN) , Gynecological Cancer Collaborative Registry (GCCR), Sarcoma Collaborative Registry (SARCR), Melanoma Collaborative Registry (MELCR), Plasma Cell Dyscrasias Collaborative Registry (PDCR), Neuroendocrine Collaborative Registry (NETR), and Auxiliary Cancer Registry (ACR). The iCaRe2 group elected to use a "confederation model", as opposed to a traditional registry or network model. It was felt that these latter models implied that the registry or network would assume control of an individual Center's database. The major advantages of a confederation model include the flexibility to use selected Centers for different research projects based on a Center's resources and expertise and the ability to have different strategies to address various research questions. It was also recognized that for this model to be successful, it is essential to have a standardized approach to data collection (patient information and biospecimen annotation) and reporting. A confederation would also encourage participation of any interested Center, irrespective of its size or location. A web-based registry iCaRe2 was developed and made available to any Center to participate in data collection and storage of cancer related data.

Inclusion Criterias

Adult individuals (male and female) who have a personal diagnosis/history of cancer
Adult individuals who are able to speak English.
Adult individuals with no history of cancer for normal control registry.
...
Adult individuals (male and female) who have a personal diagnosis/history of cancer
Adult individuals who are able to speak English.
Adult individuals with no history of cancer for normal control registry.
19 years of age or older.
Able to provide consent.
Adult individuals who have a risk for developing cancer or suspicious clinical findings

Exclusion Criterias

Anyone who does not meet the above inclusion criteria for this project.
Non-English speaking individuals.
Individuals unable to provide informed consent by virtue of cognitive impairment.
...
Anyone who does not meet the above inclusion criteria for this project.
Non-English speaking individuals.
Individuals unable to provide informed consent by virtue of cognitive impairment.
Individuals under age 19.

Locations

Norfolk, Nebraska, 68701
Omaha, Nebraska, 68114
Kansas City, Missouri, 64111
Sioux Falls, South Dakota, 57105
Fergus Falls, Minnesota, 56537
...
Norfolk, Nebraska, 68701
Omaha, Nebraska, 68114
Kansas City, Missouri, 64111
Sioux Falls, South Dakota, 57105
Fergus Falls, Minnesota, 56537
Spencer, Iowa, 51301
Kansas City, Missouri, 64118
Glens Falls, New York, 12801
Saint Joseph, Missouri, 64507
Aberdeen, South Dakota, 57401
Liberty, Missouri, 64068
Fayetteville, North Carolina, 28304
Daytona Beach, Florida, 32117
Joplin, Missouri, 64804
Kokomo, Indiana, 46902
Indianapolis, Indiana, 46256
Colorado Springs, Colorado, 80907
Louisville, Colorado, 80027
Pueblo, Colorado, 81004
Utica, New York, 13501
Yankton, South Dakota, 57078
Overland Park, Kansas, 66213
Council Bluffs, Iowa, 51503
Fredericksburg, Virginia, 22401
Westminster, Colorado, 80228
Franklin, Wisconsin, 53132
Orange City, Florida, 32763
DeLand, Florida, 32720
Moline, Illinois, 61265
Appleton, Wisconsin, 54915
Aitkin, Minnesota, 56431
Palm Coast, Florida, 32164
Holyoke, Massachusetts, 01040
Waterloo, Iowa, 50702
Yankton, South Dakota, 57078
Omaha, Nebraska, 68198
New Orleans, Louisiana, 70112
Denver, Colorado, 80210
Kalispell, Montana, 59901
Parker, Colorado, 80138
Fort Wayne, Indiana, 46845
Rutland, Vermont, 05701
Mequon, Wisconsin, 53097
Sioux Falls, South Dakota, 57105
Marshall, Minnesota, 56258
Omaha, Nebraska, 68114
Indianapolis, Indiana, 46227
Longmont, Colorado, 80501
North Platte, Nebraska, 69101
Brookfield, Wisconsin, 53045
Oshkosh, Wisconsin, 54904
Durango, Colorado, 81301
Davenport, Iowa, 52804
Scottsbluff, Nebraska, 69361
Missoula, Montana, 59802
O'Neill, Nebraska, 68763
Fargo, North Dakota, 58103
Mitchell, South Dakota, 57301
Ann Arbor, Michigan, 48109
Milwaukee, Wisconsin, 53211
Aurora, Illinois, 60504
Yorkville, Illinois, 60560
Racine, Wisconsin, 53405
Randallstown, Maryland, 21133
Brainerd, Minnesota, 56401
Portland, Maine, 04102
Lakewood, Colorado, 80228
Duluth, Minnesota, 55805
Duluth, Minnesota, 55805
Wauwatosa, Wisconsin, 53226
Westminster, Maryland, 21157
Hastings, Nebraska, 68901
Yankton, South Dakota, 57078
Pittsburgh, Pennsylvania, 15323
Kansas City, Missouri, 64086
Minot, North Dakota, 58701
Littleton, Colorado, 80122
Indianapolis, Indiana, 46219

Tracking Information

NCT #
NCT02012699
Collaborators
Not Provided
Investigators
  • Principal Investigator: Whitney Goldner, MD University of Nebraska
  • Whitney Goldner, MD University of Nebraska