Recruitment

Recruitment Status
Completed
Estimated Enrollment
16

Exclusion Criterias

Clinically significant allergy or sensitivity to medications Positive test for human immunodeficiency virus (HIV) antibodies, Hepatitis B surface antigen, or Hepatitis C antibody.
Any disorder that may interfere with drug absorption.
Clinically significant abnormalities on physical examination, medical history, ECG , vital signs, laboratory values, or unstable medical or psychiatric illness
...
Clinically significant allergy or sensitivity to medications Positive test for human immunodeficiency virus (HIV) antibodies, Hepatitis B surface antigen, or Hepatitis C antibody.
Any disorder that may interfere with drug absorption.
Clinically significant abnormalities on physical examination, medical history, ECG , vital signs, laboratory values, or unstable medical or psychiatric illness
History of exposure to any radiation >15 mSv/year (e.g., occupational or radiation therapy) over the past year.
Pregnant or breast feeding.

Summary

Conditions
Healthy
Type
Interventional
Phase
Phase 1
Design
  • Allocation: Non-Randomized
  • Intervention Model: Parallel Assignment
  • Masking: None (Open Label)
  • Primary Purpose: Basic Science

Participation Requirements

Age
Between 18 years and 50 years
Gender
Both males and females

Exclusion Criterias

Clinically significant allergy or sensitivity to medications Positive test for human immunodeficiency virus (HIV) antibodies, Hepatitis B surface antigen, or Hepatitis C antibody.
Any disorder that may interfere with drug absorption.
Clinically significant abnormalities on physical examination, medical history, ECG , vital signs, laboratory values, or unstable medical or psychiatric illness
...
Clinically significant allergy or sensitivity to medications Positive test for human immunodeficiency virus (HIV) antibodies, Hepatitis B surface antigen, or Hepatitis C antibody.
Any disorder that may interfere with drug absorption.
Clinically significant abnormalities on physical examination, medical history, ECG , vital signs, laboratory values, or unstable medical or psychiatric illness
History of exposure to any radiation >15 mSv/year (e.g., occupational or radiation therapy) over the past year.
Pregnant or breast feeding.

Locations

New Haven, Connecticut
New Haven, Connecticut

Tracking Information

NCT #
NCT02001389
Collaborators
Not Provided
Investigators
Not Provided