A Pilot Study Testing Salicylic Acid Peels Versus Glycolic Acid Peels for the Treatment of Melasma
Last updated on April 2022Recruitment
- Recruitment Status
- Active, not recruiting
- Estimated Enrollment
- 20
Inclusion Criteria
- Subjects must be willing to not apply other treatment options for melasma during the course of the study
- Subjects aged 18 years or older
- Subjects with at least a 2 x 2 cm patch of melasma on each side of the face (forehead or cheek)
- ...
- Subjects must be willing to not apply other treatment options for melasma during the course of the study
- Subjects aged 18 years or older
- Subjects with at least a 2 x 2 cm patch of melasma on each side of the face (forehead or cheek)
- Subjects in general good health
- Subjects must be willing and able to understand and provide informed consent for the use of their tissue and communicate with the investigator
Exclusion Criteria
- Subjects who have concurrent active uncontrolled disease to facial area (i.e uncontrolled acne)
- Subjects with a history of abnormal scarring
- Subjects who have had a chemical peel in the past 3 months
- ...
- Subjects who have concurrent active uncontrolled disease to facial area (i.e uncontrolled acne)
- Subjects with a history of abnormal scarring
- Subjects who have had a chemical peel in the past 3 months
- Subjects who have used a prescribed retinoid in the past 3 months
- Subjects with a history of abnormal wound healing
- Subjects diagnosed with mental illness
- Subjects who are pregnant and/or lactating
- Subjects under 18 years of age
- Subjects with a bleeding disorder
- Subjects who are unable to understand the protocol or to give informed consent
Summary
- Conditions
- Melanosis
- Type
- Interventional
- Design
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
Participation Requirements
- Age
- Between 18 years and 65 years
- Gender
- Both males and females
Description
Participants in this study will be patients who are clinically diagnosed with at least a 2 x 2 cm patch of melasma on each side of their face (forehead or cheek). One half of the subject's face will be randomly selected to receive 4 treatments of 30% glycolic acid peels and the other half of the fac...
Participants in this study will be patients who are clinically diagnosed with at least a 2 x 2 cm patch of melasma on each side of their face (forehead or cheek). One half of the subject's face will be randomly selected to receive 4 treatments of 30% glycolic acid peels and the other half of the face will receive 4 treatments of 30% salicylic acid peels/ weeks 0, 4, 8, and 12. Follow up visit will be at week 16. This study is a pilot study designed to determine feasibility of these procedures.
Inclusion Criteria
- Subjects must be willing to not apply other treatment options for melasma during the course of the study
- Subjects aged 18 years or older
- Subjects with at least a 2 x 2 cm patch of melasma on each side of the face (forehead or cheek)
- ...
- Subjects must be willing to not apply other treatment options for melasma during the course of the study
- Subjects aged 18 years or older
- Subjects with at least a 2 x 2 cm patch of melasma on each side of the face (forehead or cheek)
- Subjects in general good health
- Subjects must be willing and able to understand and provide informed consent for the use of their tissue and communicate with the investigator
Exclusion Criteria
- Subjects who have concurrent active uncontrolled disease to facial area (i.e uncontrolled acne)
- Subjects with a history of abnormal scarring
- Subjects who have had a chemical peel in the past 3 months
- ...
- Subjects who have concurrent active uncontrolled disease to facial area (i.e uncontrolled acne)
- Subjects with a history of abnormal scarring
- Subjects who have had a chemical peel in the past 3 months
- Subjects who have used a prescribed retinoid in the past 3 months
- Subjects with a history of abnormal wound healing
- Subjects diagnosed with mental illness
- Subjects who are pregnant and/or lactating
- Subjects under 18 years of age
- Subjects with a bleeding disorder
- Subjects who are unable to understand the protocol or to give informed consent
Tracking Information
- NCT #
- NCT01976286
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Murad Alam, MD Northwestern University
- Murad Alam, MD Northwestern University