Recruitment

Recruitment Status
Completed
Estimated Enrollment
40

Inclusion Criterias

patients with suspected acute myocarditis and otherwise unremarkable cardiac history
patients with suspected acute myocarditis and otherwise unremarkable cardiac history

Exclusion Criterias

contraindications for MR imaging
exclusion of CAD in invasive coronary angiography
pregnancy
contraindications for MR imaging
exclusion of CAD in invasive coronary angiography
pregnancy

Summary

Conditions
Suspected Acute Myocarditis
Type
Observational
Design
  • Observational Model: Cohort
  • Time Perspective: Prospective

Participation Requirements

Age
Between 16 years and 125 years
Gender
Both males and females

Description

Cardiac magnetic resonance (CMR) is an established non-invasive diagnostic tool for acute and chronic myocarditis. Established CMR criteria for diagnosing myocarditis are edema on black-blood T2-weighted imaging, relative contrast enhancement seen on T1-weighted imaging for assessment of hyperemia, ...

Cardiac magnetic resonance (CMR) is an established non-invasive diagnostic tool for acute and chronic myocarditis. Established CMR criteria for diagnosing myocarditis are edema on black-blood T2-weighted imaging, relative contrast enhancement seen on T1-weighted imaging for assessment of hyperemia, and late contrast-agent enhancement seen with inversion recovery late enhancement technique for visualization of myocardial fibrosis. Recently, tissue characterization based on calculation of myocardial T1 relaxation time (T1 mapping) as well as T1-derived extracellular volume fraction has become available. Recently, reference values for myocardial T1 relaxation times at 3T for healthy volunteers were published for CMR. However, to date no comprehensive data for multiparametric CMR in patients with suspected myocarditis at 3 Tesla is available. Therefore, the purpose of this prospective study was to evaluate the diagnostic value of CMR at 3T in patients with suspected acute myocarditis using a multiparametric CMR approach including T1 mapping as novel tool for tissue characterization. CMR will be performed within 7 days after hospital admission for "suspected acute myocarditis".

Inclusion Criterias

patients with suspected acute myocarditis and otherwise unremarkable cardiac history
patients with suspected acute myocarditis and otherwise unremarkable cardiac history

Exclusion Criterias

contraindications for MR imaging
exclusion of CAD in invasive coronary angiography
pregnancy
contraindications for MR imaging
exclusion of CAD in invasive coronary angiography
pregnancy

Locations

Bonn, NRW, 53127
Bonn, NRW, 53127

Tracking Information

NCT #
NCT01962584
Collaborators
Not Provided
Investigators
Not Provided