Recruitment

Recruitment Status
Completed
Estimated Enrollment
410

Inclusion Criterias

Worsening chronic heart failure (WCHF) requiring hospitalization (or intravenous diuretic treatment for HF without hospitalization) with initiation of study treatment after clinical stabilization
Left ventricular ejection fraction (LVEF) <45% by echocardiography at randomization
Worsening chronic heart failure (WCHF) requiring hospitalization (or intravenous diuretic treatment for HF without hospitalization) with initiation of study treatment after clinical stabilization
Left ventricular ejection fraction (LVEF) <45% by echocardiography at randomization

Exclusion Criterias

Intravenous inotropes at any time after hospitalization
Intravenous inotropes at any time after hospitalization

Summary

Conditions
Heart Failure
Type
Interventional
Phase
Phase 2
Design
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
  • Primary Purpose: Treatment

Participation Requirements

Age
Between 18 years and 125 years
Gender
Both males and females

Inclusion Criterias

Worsening chronic heart failure (WCHF) requiring hospitalization (or intravenous diuretic treatment for HF without hospitalization) with initiation of study treatment after clinical stabilization
Left ventricular ejection fraction (LVEF) <45% by echocardiography at randomization
Worsening chronic heart failure (WCHF) requiring hospitalization (or intravenous diuretic treatment for HF without hospitalization) with initiation of study treatment after clinical stabilization
Left ventricular ejection fraction (LVEF) <45% by echocardiography at randomization

Exclusion Criterias

Intravenous inotropes at any time after hospitalization
Intravenous inotropes at any time after hospitalization

Locations

Ashkelon, 7830604
Szekesfehervar, 8000
Roeselare, 8800
Lodz, 92-213
Bruxelles - Brussel, 1200
...
Ashkelon, 7830604
Szekesfehervar, 8000
Roeselare, 8800
Lodz, 92-213
Bruxelles - Brussel, 1200
Malmö, 205 02
Yokohama, Kanagawa, 236-0051
Tiberias, 1528001
Brugge, 8000
Krakow, 31-202
Wien, 1220
Montreal, Quebec, H2W 1T8
Milano, Lombardia, 20149
Yao, Osaka, 581-0011
Sherbrooke, Quebec, J1G 2E8
Kromeriz, 767 01
Ostrava, 708 52
Hamburg, 20246
Veldhoven, 5504 DB
Milano, Lombardia, 20017
Ancona, Marche, 60126
Mechelen, 2800
Fort Lauderdale, Florida, 33308
Majadahonda, Madrid, 28222
Frankfurt, Hessen, 60596
Hannover, Niedersachsen, 30625
Köln, Nordrhein-Westfalen, 50924
Kumamoto, 862-8505
Atlanta, Georgia, 30342
Brescia, Lombardia, 25123
Petah Tikva, 4941492
Helsingborg, 251 87
Minneapolis, Minnesota, 55422
Naples, Florida, 34102
Praha 2, 12808
L'Hospitalet de Llobregat, Barcelona, 08907
Sofia, 1233
Erfurt, Thüringen, 99089
Aalborg, 9000
Zürich, 8091
Meguro-ku, Tokyo, 152-8902
Örebro, 701 85
Sendai, Miyagi, 981-3133
La Tronche, 38700
Minato-ku, Tokyo, 106-0031
Toronto, Ontario, M5B 1W8
Charleston, South Carolina, 29425
Zrifin, 7030000
St. Pölten, Niederösterreich, 3100
Praha 6, 169 02
Wilmington, Delaware, 19803
Columbus, Ohio, 43210
Naha, Okinawa, 902-8511
Lille Cedex, 59037
Bergamo, Lombardia, 24127
Gilly, 6060
Pessac, 33604
Fairfield, Ohio, 45014
Nashville, Tennessee, 37232-8802
Tel Aviv, 6423906
Leeuwarden, 8901 BR
Sofia, 1202
Como, Lombardia, 22020
Rehovot, 7610001
Stockholm, 118 83
Yokosuka, Kanagawa, 238-8567
Nagasaki, 850-8555
Fountain Valley, California, 92708
Stara Zagora, 6000
Nea Ionia, 14233
BRON Cedex, 69677
HUY, 4500
Athens, 11527
Paris Cedex 15, 75908
Sofia, 1309
Karlstad, 651 85
Linköping, 581 85
Budapest, 1032
MOL, 2400
Rouen, 76031
Toyama, 930-8550
Heerenveen, 8441 PW
Milwaukee, Wisconsin, 53215
Taipei, 11217
Kanazawa, Ishikawa, 920-8650
Macon, Georgia, 31201
Viborg, 8800
Bruderholz, 4101
Valencia, 46026
Singapore, 308433
Buffalo, New York, 14215
Bad Homburg, Hessen, 61348
Jerusalem, 9103102
Pavia, Lombardia, 27100
Bialystok, 15-276
Hiroshima, 734-8530
Saint-Jean-sur-Richelieu, Quebec, J3A 1C3
Singapore, 169609
Stevenage, Hertfordshire, SG1 4AB
Salzburg, 5020
Hadera, 3810101
Barcelona, 08023
New Taipei City, 220
Tokushima, 770-8539
Valencia, 46010
Praha 4, 140 21
Chesterfield, Derbyshire, S44 5DX
Liestal, Basel-Landschaft, 4410
Aarhus N, 8200
Afula, 1834111
Barcelona, 08003
Himeji, Hyogo, 670-0981
Prahran, Victoria, 3181
Verona, Veneto, 37045
Taipei, 10016
Singapore, 119228
Sofia, 1527
Sagamihara, Kanagawa, 252-5188
Germantown, Tennessee, 38138
Hobart, Tasmania, 7000
Detroit, Michigan, 48202
Münster, Nordrhein-Westfalen, 48149
München, Bayern, 80331
Darlinghurst, New South Wales, 2010
Kaohsiung, 813
Deventer, 7416 SE
Jackson, Mississippi, 39216-4505
Kistarcsa, H-2143
New Orleans, Louisiana, 70112-1396
Fukui, 910-8526
Amsterdam, 1105 AZ
Linz, Oberösterreich, 4020
Montreal, Quebec, H1T 1C8
Olsztyn, 10-010
Jacksonville, Florida, 32209
Quebec, G1V 4G5
Graz, Steiermark, 8036
Praha 10, 10034
Hellerup, DK-2900
Poznan, 61-848
Santander, Cantabria, 39008
Slany, 274 01
Arezzo, Toscana, 52040
Singapore, 768828
Gent, 9000
Warszawa, 02-507
Hradec kralove, 500 05
Greifswald, Mecklenburg-Vorpommern, 17475
Takatsuki, Osaka, 569-1096
Lugano, 6900
Legnica, 59-220
Komatsushima, Tokushima, 773-8502
Homburg, Saarland, 66424
Ureshino, Saga, 843-0393
Milano, Lombardia, 20138
Iizuka, Fukuoka, 820-8505
Seoul, 138-736

Tracking Information

NCT #
NCT01951625
Collaborators
Not Provided
Investigators
Study Director: Bayer Study Director Bayer