Recruitment

Recruitment Status
Completed

Inclusion Criterias

no known allergies to drugs
ASA 1=2 patients
18-65 yo female
...
no known allergies to drugs
ASA 1=2 patients
18-65 yo female
scheduled for elective hysterectomy

Exclusion Criterias

history of chronic pain treatment
pregnancy
history of diabetes
history of chronic pain treatment
pregnancy
history of diabetes

Summary

Conditions
Pain
Type
Interventional
Phase
Phase 4
Design
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
  • Primary Purpose: Treatment

Participation Requirements

Age
Between 18 years and 65 years
Gender
Only females

Description

Abdominal hysterectomy is associated with moderate to severe postoperative pain, effective analgesia after hysterectomy essential and several techniques are used such as administration of opioids, nonsteroidal anti-inflammatory drugs and wound infiltration of local anaesthetics. Different local anae...

Abdominal hysterectomy is associated with moderate to severe postoperative pain, effective analgesia after hysterectomy essential and several techniques are used such as administration of opioids, nonsteroidal anti-inflammatory drugs and wound infiltration of local anaesthetics. Different local anaesthetics can be used for the wound infiltration techniques.Ifiltration of the surgical wound with bupivacaine following outpatient provides pain relief in the postoperative period , allows the early discharge from the outpatient surgical units.There has been increased interest in administration of analgesic prior to surgical injury. Dexmedetomidine is a highly selective alpha-2 adrenergic agonist with sedative , anxiolytic, analgesic, sympatholytic and antihypertensive effects.Dexmedetomidine has been used intravenously before initiation of anaesthesia and it has shown to provide some analgesic effect after surgery but there were some adverse hemodynamic effects. Surgical wound administration of dexmedetomidine may be useful to avoid the adverse haemodynamic effects of intravenous administration while still providing the postoperative analgesia.

Inclusion Criterias

no known allergies to drugs
ASA 1=2 patients
18-65 yo female
...
no known allergies to drugs
ASA 1=2 patients
18-65 yo female
scheduled for elective hysterectomy

Exclusion Criterias

history of chronic pain treatment
pregnancy
history of diabetes
history of chronic pain treatment
pregnancy
history of diabetes

Locations

Kayseri, 38039
Kayseri, 38039

Tracking Information

NCT #
NCT01929252
Collaborators
Not Provided
Investigators
  • Principal Investigator: Fatih M. Kurt, Resident TC Erciyes University Study Director: Ayse Ulgey, Asst. Prof TC Erciyes University
  • Fatih M. Kurt, Resident TC Erciyes University Study Director: Ayse Ulgey, Asst. Prof TC Erciyes University