Recruitment

Recruitment Status
Completed
Estimated Enrollment
24

Inclusion Criterias

Elevated suspiciousness (PANSS,P6≥3)
meets criteria for ARMS (at Risk Mental State, assessed by CAARMS)
Elevated suspiciousness (PANSS,P6≥3)
meets criteria for ARMS (at Risk Mental State, assessed by CAARMS)

Summary

Conditions
  • APS
  • ARMS
  • Prodromal Symptoms
Type
Interventional
Design
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Single (Outcomes Assessor)
  • Primary Purpose: Prevention

Participation Requirements

Age
Between 12 years and 25 years
Gender
Both males and females

Description

24 adolescents and young adults between the ages of 12 and 25 who are at high risk of developing psychosis and exhibit paranoid ideation will be recruited to participate in a pilot randomized controlled trial. Subjects will be randomly assigned to the intervention (GF-CBT)or control (symptom monitor...

24 adolescents and young adults between the ages of 12 and 25 who are at high risk of developing psychosis and exhibit paranoid ideation will be recruited to participate in a pilot randomized controlled trial. Subjects will be randomly assigned to the intervention (GF-CBT)or control (symptom monitoring) groups. GF-CBT is based on a cognitive neuropsychiatric model of delusions, and incorporates recent developments in learning and cognitive theories. GF-CBT consists of individual, group, and family group sessions. The three-part program teaches adolescents and family members Cognitive Behavioral skills that they can continue using on their own after completion of the program. Preliminary efficacy of the intervention will be evaluated using standardized measures by blind evaluators conducted at baseline, post-treatment, and post-termination follow-up over the next 2 years. Hypotheses: (a) GF-CBT will be associated with: high rate of remission from "at risk status" and low rates of transition to psychosis (defined by CAARMS criteria); greater improvements in severity of symptoms; and improved functioning; (b) decrease in family members'level of stress, and improved coping; (c) Family members will demonstrate proficiency in CBT Skills.

Inclusion Criterias

Elevated suspiciousness (PANSS,P6≥3)
meets criteria for ARMS (at Risk Mental State, assessed by CAARMS)
Elevated suspiciousness (PANSS,P6≥3)
meets criteria for ARMS (at Risk Mental State, assessed by CAARMS)

Locations

New York, New York, 10065
New York, New York, 10065

Tracking Information

NCT #
NCT01923701
Collaborators
Sidney R. Baer, Jr. Foundation
Investigators
  • Principal Investigator: Yulia Landa, Psy.D., M.S. Icahn School of Medicine at Mount Sinai
  • Yulia Landa, Psy.D., M.S. Icahn School of Medicine at Mount Sinai