Recruitment

Recruitment Status
Unknown status

Inclusion Criterias

Subjective difficulties with memory or concentration
Aged 18-60 Years
History of Psychosis
...
Subjective difficulties with memory or concentration
Aged 18-60 Years
History of Psychosis
Schizophrenia

Exclusion Criterias

Substance misuse in the last 3 months
History of head injury resulting in loss of consciousness
Substance misuse in the last 3 months
History of head injury resulting in loss of consciousness

Summary

Conditions
  • Psychosis
  • Schizophrenia
Type
Interventional
Design
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Triple (Participant, Investigator, Outcomes Assessor)
  • Primary Purpose: Treatment

Participation Requirements

Age
Between 18 years and 60 years
Gender
Both males and females

Description

The aim of this project is to undertake a randomized placebo controlled trial of cognitive remediation therapy (CRT) that focuses on working memory training in a sample of community based patients with schizophrenia. Pre and Post neuropsychological assessment and Magnetic Resonance Imagery (MRI) wil...

The aim of this project is to undertake a randomized placebo controlled trial of cognitive remediation therapy (CRT) that focuses on working memory training in a sample of community based patients with schizophrenia. Pre and Post neuropsychological assessment and Magnetic Resonance Imagery (MRI) will be used to determine the effects of CR training on Neuropsychological performance Brain Structure using voxel-based morphometry (VBM) Brain function using functional MRI (fMRI) Social and occupational functioning The cognitive remediation intervention is a computerised programme whose training level is dynamically varied to suit participants individual ability level. Motivation to learn and generalization to real world function are a particular focus of the intervention and are supported with ongoing therapist interaction in addition to personal training.

Inclusion Criterias

Subjective difficulties with memory or concentration
Aged 18-60 Years
History of Psychosis
...
Subjective difficulties with memory or concentration
Aged 18-60 Years
History of Psychosis
Schizophrenia

Exclusion Criterias

Substance misuse in the last 3 months
History of head injury resulting in loss of consciousness
Substance misuse in the last 3 months
History of head injury resulting in loss of consciousness

Locations

Dublin, 8
Dublin, 8

Tracking Information

NCT #
NCT01903707
Collaborators
Health Research Board, Ireland
Investigators
  • Principal Investigator: Gary J Donoghoe, DClin Psych PhD Trinity College Dublin, Ireland
  • Gary J Donoghoe, DClin Psych PhD Trinity College Dublin, Ireland