Recruitment

Recruitment Status
Active, not recruiting

Summary

Conditions
  • Atherosclerosis
  • Blood Pressure
  • Glucose Metabolism Disorders
  • Lipid Metabolism Disorders
  • Overweight
Type
Interventional
Phase
Not Applicable
Design
Allocation: Non-RandomizedIntervention Model: Parallel AssignmentIntervention Model Description: A single-centre controlled trial in which the participants are allocated to a combined physical activity and dietary intervention group and a control groupMasking: None (Open Label)Primary Purpose: Prevention

Participation Requirements

Age
Between 6 years and 9 years
Gender
Both males and females

Description

We will investigate a population sample of 512 children from the city of Kuopio, Finland. The children will be recruited in 2007-2009 when they are 7-9 years of age and when they will start the first grade in primary schools of the city of Kuopio. The children will be allocated to the combined physi...

We will investigate a population sample of 512 children from the city of Kuopio, Finland. The children will be recruited in 2007-2009 when they are 7-9 years of age and when they will start the first grade in primary schools of the city of Kuopio. The children will be allocated to the combined physical activity and dietary intervention group and the control group after baseline examinations carried out in 2007-2009. The intervention group will undergo individualized and family-based physical activity and dietary intervention, including six intervention visits, for two years. All children from the intervention and control group will be invited to 2-year follow-up examinations carried out in 2009-2011 when they are 9-11 years of age. The intervention group will continue with a less intensive physical activity and dietary intervention until 8-year follow-up examinations carried out in 2015-2017 when the participants are 15-17 years of age. The participants from the intervention and control group will continue with an open follow-up until 14-year follow-up examinations in 2021-2023 when they are 21-23 years of age. All of these study phases will include comprehensive and detailed assessments of behavioral, biological, environmental, and genetic risk factors for cardiometabolic diseases and other chronic diseases. The results of the PANIC Study will help in 1) decreasing the risk of developing cardiometabolic diseases and other chronic diseases since childhood by increasing physical activity, decreasing sedentary time, and improving diet, 2) identifying children and adolescents at increased risk of cardiometabolic diseases and other chronic diseases who would benefit most from the physical activity and dietary interventions, 3) targeting children and adolescents, particularly those at increased risk of cardiometabolic diseases and other chronic diseases, for more careful health examinations, physical activity and dietary interventions, and health follow-up, and 4) preventing cardiometabolic diseases and other chronic diseases as well as their societal consequences in adulthood.

Tracking Information

NCT #
NCT01803776
Collaborators
  • University of Jyvaskyla
  • Kuopio University Hospital
  • Kuopio Research Institute of Exercise Medicine
  • University of Turku
  • Tampere University
  • Folkhälsan Researech Center
  • University of Cambridge
  • Early Growth Genetics (EGG) Consortium
  • University of Exeter
  • University of Copenhagen
  • LongITools Consortium
  • Norwegian School of Sport Sciences
  • University of Tromso
  • University of Iceland
Investigators
Principal Investigator: Timo A Lakka, MD University of Eastern Finland, Kuopio campus