Recruitment

Recruitment Status
Completed
Estimated Enrollment
Same as current

Summary

Conditions
Sarcoma
Type
Observational
Design
Observational Model: Case-OnlyTime Perspective: Retrospective

Participation Requirements

Age
Younger than 125 years
Gender
Both males and females

Description

OBJECTIVES: To obtain a larger cohort of rhabdomyosarcoma samples (alveolar and embryonal) to establish a more accurate estimate of the frequency of particular genetic lesions. To provide the statistical power to establish an unambiguous connection between focal genetic lesions, histological subtype...

OBJECTIVES: To obtain a larger cohort of rhabdomyosarcoma samples (alveolar and embryonal) to establish a more accurate estimate of the frequency of particular genetic lesions. To provide the statistical power to establish an unambiguous connection between focal genetic lesions, histological subtype, and outcome for patients with rhabdomyosarcoma. OUTLINE: DNA samples are analyzed in solid and liquid phase for exons of all genes mutated from previous discovery. DNA is then eluted and sequenced by illumina platform.

Tracking Information

NCT #
NCT01585376
Collaborators
National Cancer Institute (NCI)
Investigators
Principal Investigator: Alberto S. Pappo, MD St. Jude Children's Research Hospital