Studying Genes in Samples From Younger Patients With Rhabdomyosarcoma
Last updated on July 2021Recruitment
- Recruitment Status
- Completed
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Sarcoma
- Type
- Observational
- Design
- Observational Model: Case-OnlyTime Perspective: Retrospective
Participation Requirements
- Age
- Younger than 125 years
- Gender
- Both males and females
Description
OBJECTIVES: To obtain a larger cohort of rhabdomyosarcoma samples (alveolar and embryonal) to establish a more accurate estimate of the frequency of particular genetic lesions. To provide the statistical power to establish an unambiguous connection between focal genetic lesions, histological subtype...
OBJECTIVES: To obtain a larger cohort of rhabdomyosarcoma samples (alveolar and embryonal) to establish a more accurate estimate of the frequency of particular genetic lesions. To provide the statistical power to establish an unambiguous connection between focal genetic lesions, histological subtype, and outcome for patients with rhabdomyosarcoma. OUTLINE: DNA samples are analyzed in solid and liquid phase for exons of all genes mutated from previous discovery. DNA is then eluted and sequenced by illumina platform.
Tracking Information
- NCT #
- NCT01585376
- Collaborators
- National Cancer Institute (NCI)
- Investigators
- Principal Investigator: Alberto S. Pappo, MD St. Jude Children's Research Hospital
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