Time Course of the Blood Pressure Lowering Effect of Liraglutide Therapy in Type 2 Diabetes
Last updated on July 2021Recruitment
- Recruitment Status
- Completed
- Estimated Enrollment
- 35
Summary
- Conditions
- Type 2 Diabetes
- Type
- Interventional
- Phase
- Phase 4
- Design
- Allocation: N/AIntervention Model: Single Group AssignmentMasking: None (Open Label)Primary Purpose: Treatment
Participation Requirements
- Age
- Between 18 years and 125 years
- Gender
- Both males and females
Description
Hypotheses Primary hypothesis • Liraglutide treatment causes a reduction in 24h BP Secondary hypothesis: The effect on BP may be mediated by an increase in natriuresis, thereby affecting ECV The effect on BP may be mediated by a decrease in arterial stiffness and central aortic pressure Purpose Prim...
Hypotheses Primary hypothesis • Liraglutide treatment causes a reduction in 24h BP Secondary hypothesis: The effect on BP may be mediated by an increase in natriuresis, thereby affecting ECV The effect on BP may be mediated by a decrease in arterial stiffness and central aortic pressure Purpose Primary purpose • To assess how quickly the antihypertensive effect of liraglutide treatment set in after initiation in patients with type 2 diabetes Secondary objectives To measure the effect of liraglutide treatment on natriuresis. To measure the effect of liraglutide treatment on ECV To measure the effect of liraglutide treatment on arterial stiffness To measure weight change after initiation of liraglutide treatment
Tracking Information
- NCT #
- NCT01499108
- Collaborators
- Novo Nordisk A/S
- Investigators
- Principal Investigator: Peter Rossing, MD Steno Diabetes Centes
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