Role of Genetics in Idiopathic Pulmonary Fibrosis (IPF)
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Familial Interstitial Pneumonia
- Familial Pulmonary Fibrosis
- Idiopathic Interstitial Pneumonia
- Idiopathic Pulmonary Fibrosis
- Type
- Observational
- Design
- Observational Model: Family-BasedTime Perspective: Cross-Sectional
Participation Requirements
- Age
- Younger than 125 years
- Gender
- Both males and females
Description
Familial Pulmonary Fibrosis (FPF) is a sub-category of the idiopathic interstitial pneumonias (IIPs). IIPs are progressive lung conditions, with limited treatment options and unknown etiology. Though the IIPs have been associated with both genetic risk factors and environmental exposures, the molecu...
Familial Pulmonary Fibrosis (FPF) is a sub-category of the idiopathic interstitial pneumonias (IIPs). IIPs are progressive lung conditions, with limited treatment options and unknown etiology. Though the IIPs have been associated with both genetic risk factors and environmental exposures, the molecular mechanism underlying disease progression remain poorly understood. This investigation seeks to identify a group of genetic loci that play a role in the development of familial interstitial pneumonia (FIP) or FPF, where 2 or more cases of IIP are seen within a family.
Tracking Information
- NCT #
- NCT01088217
- Collaborators
- University of Colorado, Denver
- Vanderbilt University
- Landspitali University Hospital
- Investigators
- Principal Investigator: David A. Schwartz, MD University of Colorado Denver; National Jewish Health